Results 111 to 120 of about 8,186,016 (282)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Impacts of the COVID-19 crisis on single-person households in South Korea. [PDF]

J Asian Econ, 2023
Jung H, Kim JH, Hong G.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Realizing person-centred care in residential care facilities for young adults with complex and chronic disabilities: the understanding, perception and beliefs of workers

, 2014
Young people living with complex and chronic disabilities who require assistance with health-related needs are rarely receiving the optimum support and care that will enable their full participation in society, or simply to live as they choose. For young
Zeeman, Heidi, Rissanen, Lauren, Ehrlich, Carolyn, Kendall, Elizabeth   +3 more
core  

Litigants in Person in Private Family Law Cases [PDF]

, 2014
This study was designed to develop the evidence base on litigants in person in private family law cases, including their behavioural drivers, experiences and support needs, and impact on the court prior to the implementation of legal aid reforms in April
Miles, J, Moorhead, Richard, Hinchly, Victoria, Hunter , Rosemary, Moorhead, R, Trinder, Liz, Miles, Jo, Sefton, Mark, Hinchly, V, Hitchings, E, Trinder, L, Pearce, J, Bader, Kay, Hunter, R, Smith , Leanne, Miles, Joanna, Pearce, Julia, Hunter, Rosemary, Bader, K, Hitchings, Emma, Sefton, M, Moorhead , Richard, Smith, Leanne, Smith, L   +23 more
core  

One single-person bicycling enhances interpersonal cooperation via increasing interpersonal neural synchronization in left frontal cortex. [PDF]

Hum Brain Mapp, 2023
Li L, Wang H, Lin Y, Li X.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Advancing Person-Centred Learning in Higher Education: Reflections and Lessons from the LearnPCC Conference

LearnPCC scientific conference held in Gothenburg, Sweden, on 12–13 December 2024The inaugural LearnPCC scientific conference was held in Gothenburg, Sweden, on 12–13 December 2024. Organised by the Centre for Person-Centred Care (GPCC) at the University
LearnPCC Conference 1 2024 Göteborg
core  

Edward T. Person in his military uniform

, 2010
Edward T.

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source