Results 181 to 190 of about 735,964 (249)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review. [PDF]

open access: yesHealth Promot J Austr
de Jesus Silva TR   +5 more
europepmc   +1 more source

The Living Situation of Single Persons

open access: yesKazoku syakaigaku kenkyu, 2019
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

IHPP: Improved Human Parts as Points for Multi-Person Pose Regression. [PDF]

open access: yesSensors (Basel)
Xu H   +6 more
europepmc   +1 more source

Are societies becoming more self-centric? Evidence from five decades of popular music spanning three continents. [PDF]

open access: yesPLoS One
Golubickis M   +8 more
europepmc   +1 more source

A hybrid in-person and online group singing program for older adults with breathing limitations: A pilot mixed-methods study. [PDF]

open access: yesCan J Respir Ther
Marquis N   +6 more
europepmc   +1 more source

Species diversity and human biting rates of malaria and dengue vectors in central and northern Benin. [PDF]

open access: yesTrop Med Health
Hoyochi I   +11 more
europepmc   +1 more source

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