Results 91 to 100 of about 9,727,209 (283)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Performance Investigation on SITP’s 60 K High Frequency Single-Stage Coaxial Pulse Tube Cryocoolers.

open access: yes, 2008
Presented at the 16th International Cryocooler Conference, held May 17-20, 2008 in Atlanta, Georgia.A series of 60 K high frequency single-stage coaxial pulse tube cryocoolers has been developed to provide reliable low-noise cooling at 60 K for space ...
Yang, K. X.   +5 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Single Stage Laparoscopic Orchiopexy for Impalpable Low Abdominal Undescended Testis in Children- Analysis of Outcome

open access: yesJournal of Islamic International Medical College
Objective: To evaluate clinical efficacy of single stage laparoscopic orchiopexy by modified Prentiss procedure for the treatment of impalpable undescended testis within 2.5 cm from deep ring in children.
Mumtaz H Khan , Amna H Khan Naila Yaqub
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Single-Stage Step-Down Power Factor Corrector without Full-Bridge Rectifier

open access: yesApplied Sciences
In this paper, a single-stage step-down power factor corrector without a full-bridge rectifier is developed, which is designed to operate in discontinuous conduction mode (DCM).
Kuo-Ing Hwu, Jenn-Jong Shieh, Yu-Ping He
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Single Stage sounding Rocket S-500

open access: yesAntarctic Record, 1979
A single stage sounding rocket S-500 is under development by Institute of Space and Aeronautical Science, University of Tokyo.It will cover 200-400 km altitude range as a substitute for the current K-9M and K-10 rockets. It can reach 350 km altitude with
Tamiya NOMURA   +2 more
doaj   +1 more source

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