Results 151 to 160 of about 2,302,248 (265)

Clinical efficacy of membrane anatomy-based 3D laparoscopic partial nephrectomy in a single stage for the treatment of ruptured renal angiomyolipoma. [PDF]

Front Oncol
Xiao J, Zheng H, Liu Y, Chen Z, Luo F, Wu G, Ye S, Li P, Kang T, Luo H, Lai C, Ye D.   +11 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Single-stage surgical modification for neonatal aortic coarctation and ventricular septal defect: a case report. [PDF]

Eur Heart J Case Rep
Yang X, Xing P, Hou K, Chen R, Pan S.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Single-Stage Surgical Treatment of Concurrent Meniere's Disease and Superior Semicircular Canal Dehiscence: A Case Report. [PDF]

Cureus
Nguyen NVP, Ng N, Liaw J.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Single-Stage Flexor Tendon Reconstruction Using Tendon Grafting Versus Turnover Tendon Split-Lengthening Technique. [PDF]

J Hand Surg Glob Online
Karagergou E, Baxevanou M, Moysiadou A, Givissis A, Sachinis NP, Givissis P.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Single-Stage Paramedian Forehead Flap

Actas Dermo-Sifiliográficas (English Edition), 2017
A, Martinez-Lopez, I, Perez-Lopez, E, Garcia-Dura, J, Tercedor-Sanchez   +3 more
openaire   +2 more sources

Single-stage laparotomy for intracardiac leiomyomatosis without open-heart surgery: a case report. [PDF]

BMC Cardiovasc Disord
Sheibani S, Wadji MB, Hosseini S, Pouraliakbar H, Hesami M, Hosseini Jebelli SF, Roudini K, Rezvani A, Alizadehasl A.   +8 more
europepmc   +1 more source