Results 61 to 70 of about 4,660 (292)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Simplified Four-Level Inverter-Based Dynamic Voltage Restorer With Single DC Power Source

open access: yesIEEE Access, 2019
This paper proposes a simplified four-level (S4L) inverter based dynamic voltage restorer (DVR). In the proposed configuration, the dual buck stage can output full, two thirds, and one third of dc link voltage.
Jian Ye   +4 more
doaj   +1 more source

POWER CONDITIONING UNIT FOR SMALL SCALE HYBRID PV-WIND GENERATION SYSTEM [PDF]

open access: yes, 2011
Small-scale renewable energy systems are becoming increasingly popular due to soaring fuel prices and due to technological advancements which reduce the cost of manufacturing.
AHMED-MAHMOUD, ASHRAF
core  

Modified SPWM Control for a Single-Stage Differential Boost Inverter Applied in a BESS

open access: yes, 2021
This study aims to implement a single-stage differential boost inverter (SSDBI) applied in a single-stage battery energy storage system (BESS) topology that can supply power from a lower-voltage battery module to an alternating current (AC) load ...
Yu-Lin Lee   +4 more
core   +1 more source

Super twisting sliding mode controller for multi-functional grid-connected inverter in photovoltaic system [PDF]

open access: yesArchives of Electrical Engineering
In this paper, the performance of a super twisting sliding mode controller (STSMC) is investigated for a multifunctional single-stage inverter that connects a photovoltaic (PV) system to the three-phase utility grid supplying the non-linear load. In this
Mahla Dehghani   +3 more
doaj   +1 more source

A transformerless three‐level three‐phase boost PWM inverter for PV applications

open access: yesIET Power Electronics, 2021
Multilevel converters have seen rising demands in the past decades, due to their increased power ratings, enhanced power quality, low switching losses and reduced electromagnetic interference.
Aswin Palanisamy   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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