Results 111 to 120 of about 5,143,829 (287)

Valve Replacement in Children with Single Ventricle Physiology.

, 2020
Severe atrioventricular valve (AVV) or semilunar valve (SLV) regurgitation in the setting of a single ventricle physiology may proceed to valve replacement if repair strategies fail. Outcome data for these children are limited. We present transplant-free
St Louis, James D, Kochilas, Lazaros, Sarvestani, Amber Leila, Thomas, Amanda S, Alshami, Noor, Raghuveer, Geetha   +5 more
core  

Long-term outcomes of heart transplantation in adults with congenital heart disease: The impact of single-ventricle versus biventricular physiologyCentral MessagePerspective

JTCVS Open
Objective: Congenital heart disease is a risk factor for mortality after orthotopic heart transplantation; however, the impact of preoperative circulation type and primary congenital heart disease diagnosis remains poorly delineated.
Alice V. Vinogradsky, BA, Stephanie N. Nguyen, MD, Krushang Patel, MD, Matthew Regan, MS, Kelly M. Axsom, MD, Matthew J. Lewis, MD, Gabriel Sayer, MD, Nir Uriel, MD, MSc, Yoshifumi Naka, MD, PhD, Andrew B. Goldstone, MD, PhD, Koji Takeda, MD, PhD   +10 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Double-Inlet Single Ventricle with Malposed Great Arteries [PDF]

Arquivos Brasileiros de Cardiologia, 2019
Paulo Andrade, Danilo Santos, Magna Moreira, Adail Almeida   +3 more
doaj   +3 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Finite element analysis of the human left ventricle in diastole and systole [PDF]

, 1997
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Previously, at Brunel University, two computer programs had been developed to facilitate the analysis of the diastolic material properties of the human left
Beecham, MC
core   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves [PDF]

, 2000
Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH, Lincoln, C, Vogel, M, Ho, SY   +3 more
core  

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

THE ELECTROCARDIOGRAM IN SINGLE VENTRICLE [PDF]

Heart, 1963
openaire   +2 more sources