Results 261 to 270 of about 7,078,310 (387)

Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients With Single Ventricle/Hypoplastic Left Heart Syndrome. [PDF]

J Gene Med
Qu HQ, Ostberg K, Slater DJ, Wang F, Snyder J, Hou C, Connolly JJ, March M, Glessner JT, Kao C, Hakonarson H.   +10 more
europepmc   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Hepatic vein-derived factors may affect pulmonary arteriovenous malformations after single ventricle palliation by modulating vascular cell behavior. [PDF]

Sci Rep
González-Teshima LY, Hakamada K, Murata K, Nakagawa R, Baba S, Ide Y, Okamura M, Ikai A, Ikeda T, Minatoya K, Hagiwara M, Ikegawa M, Masumoto H.   +12 more
europepmc   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Galectin-3 in single ventricle physiology: insights into fibrosis and functional impairment after Fontan procedure

Magdalena Kowalczyk, Mirosław Kowalski
openalex   +2 more sources

Common atrioventricular valve failure during single ventricle palliation†

European Journal of Cardio-Thoracic Surgery, 2017
Gregory King, T. Gentles, D. Winlaw, R. Cordina, A. Bullock, L. Grigg, N. Alphonso, D. Radford, D. Zannino, E. Buratto, Y. D'udekem   +10 more
semanticscholar   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

A Retrospective Study on the Imaging Spectrum of Functional Single Ventricle and Its Associations. [PDF]

Indian J Radiol Imaging
Niva B, Rajeshkannan R.
europepmc   +1 more source

Surgical repair of single ventricle

The Journal of Thoracic and Cardiovascular Surgery, 1973
R N, Edie, K, Ellis, W M, Gersony, E, Krongrad, F O, Bowman, J R, Malm   +5 more
openaire   +2 more sources

Optimization of the Assisted Bidirectional Glenn Procedure for First Stage Single Ventricle Repair

World journal for pediatric & congenital heart surgery, 2018
Aekaansh Verma, M. Esmaily, J. Shang, R. Figliola, J. Feinstein, T. Hsia, A. Marsden   +6 more
semanticscholar   +1 more source