Results 31 to 40 of about 34,269 (219)

The effect of non-singular term (T-stress) on mode I/III cracking parameters of brittle materials, Numerical and experimental study using different beam and disc shape specimens made of marble rock

Forces in Mechanics
This study focuses on less-studied mode I/III fracture cracking behaviour. Seven specimens (ENDC, DNDC, SCB, ENDB, ATPB, TPB-IC, and SENB) were analyzed numerically and experimentally. Results show in pure mode-I, the specimens show identical KIc values (1.22 to 1.54 MPa√m).
Amir Mousavi, M.R.M. Aliha, Hadi Khoramishad, Hamid Reza Karimi   +3 more
openaire   +2 more sources

An efficient method for computation of singular and higher order terms of a crack-tip stress field

, 2005
A recently developed semi-analytical method, called scaled boundary finite element method, is applied to evaluate the coefficients of stress field at a crack-tip for two-dimensional linear-elastic cracked structures.
S. Shrestha, M. Ohga
semanticscholar   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

An enhanced method for reconstruction of full SIF spectrum for near-ground measurements

International Journal of Applied Earth Observations and Geoinformation
Recently the applications of remotely sensed Solar-Induced chlorophyll Fluorescence (SIF) in the study of photosynthesis, stress conditions, and gross primary production have increased significantly.
Feng Zhao, Mateen Tariq, Weiwei Ma, Zhenfeng Wu, Yanshun Zhang   +4 more
doaj   +1 more source

An Effect of the First Non-Singular Term of the Williams Asymptotic Expansion to the Stability of the Bi-Material Orthotropic Notch

, 2013
The domain of the generalized stress intensity factors dominance ahead of the notch tip can be rather small with respect to the length of the perturbing cracks initiated from the tip of the notch.
T. Profant, J. Klusák, O. Ševeček, M. Kotoul, M. Hrstka, P. Marcián   +5 more
semanticscholar   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

Advanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios, Anthony Gonzalez, Aleksander Aleman, Tyler Dolmetsch, Tanaji Paul, Arvind Agarwal   +5 more
wiley   +1 more source