Results 51 to 60 of about 3,199,416 (302)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mathematical Modelling and AnalysisFor Volterra integro-differential equations (VIDEs) with weakly singular kernels, their solutions are singular at the initial time. This property brings a great challenge to traditional numerical methods. Here, we investigate the numerical approximation
ZhiPeng Liu, DongYa Tao, Chao Zhang
doaj +1 more source
Removability of singularities of $A$-harmonic functions
Differential and Integral Equations, 1999 The main result of this paper consists in three theorems. The first two theorems state new Caccioppoli-type estimates for the second order quasilinear partial differential equations. The third one -- removability theorem -- identifies removable singularities of \(A\)-harmonic functions making use of the estimates derived in the previous two theorems.
L. BUDNEY +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Singular polynomials from orbit spaces [PDF]
, 2012 We consider the polynomial representation S(V*) of the rational Cherednik algebra H_c(W) associated to a finite Coxeter group W at constant parameter c.
Feigin, M., Silantyev, A.
core +1 more source
Geometric Singularities of the Stokes Problem
Abstract and Applied Analysis, 2014 When the domain is a polygon of ℝ2, the solution of a partial differential equation is written as a sum of a regular part and a linear combination of singular functions.
Nejmeddine Chorfi
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p-adic singular integrals and their commutators in generalized Morrey spaces
Journal of Inequalities and Applications, 2019 For a prime number p, let Qp $\mathbb{Q}_{p}$ be the field of p-adic numbers. In this paper, we establish the boundedness of a class of p-adic singular integral operators on the p-adic generalized Morrey spaces.
Hui X. Mo +3 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Dependence of GaN Exciton Energy on Temperature
CrystalsIn this paper, we investigate the relationship between GaN exciton energy and temperature by using high-quality, strain-free GaN epilayers. Traditional models, such as Varshni’s model and the Bose–Einstein model, are primarily based on empirical fitting ...
Xiancheng Liu +8 more
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Removable singularities for subharmonic functions [PDF]
Pacific Journal of Mathematics, 1991 Let \(\Omega\) be an open set in \({\mathbb{R}}^ n\) \((n\geq 3)\) and \(S\) be a \(C^ 2\) \((n-1)\)-dimensional manifold in \(\Omega\). Let \(\alpha\in (0,n-2)\) and \(E\) be a compact subset of \(S\) of zero \(\alpha\)-dimensional Hausdorff measure. In this paper it is shown that, if \(s\) is subharmonic in \(\Omega\setminus E\) and satisfies \(s(X ...
openaire +2 more sources