Results 31 to 40 of about 6,962 (263)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Elliptic perturbations for Hammerstein equations with singular nonlinear term

open access: yesElectronic Journal of Differential Equations, 2006
We consider a singular elliptic perturbation of a Hammerstein integral equation with singular nonlinear term at the origin. The compactness of the solutions to the perturbed problem and, hence, the existence of a positive solution for the ...
Giuseppe Maria Coclite   +1 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Solving one pseudo-Volterra integral equation

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
In this paper, we study the solvability of a second - kind pseudo-Volterra integral equation. By replacing the right - hand side and the unknown function, the integral equation is reduced to an integral equation, the kernel of which is not «compressible»
M.T. Kosmakova   +4 more
doaj   +1 more source

A parallel‐plate waveguide antenna radiating through a perfectly conducting wedge

open access: yesIET Microwaves, Antennas & Propagation, 2021
Parallel‐plate waveguide antennas hosted in an electrically perfectly conducting wedge are studied. The analysis relies on an exact singular integral equation formulation.
John L. Tsalamengas   +1 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Bernoulli Polynomials Method for Solving Integral Equations with Singular Kernel

open access: yesمجلة بغداد للعلوم
There is always an interest in an effective technique to generate a numerical solution of integral equations with singular or weakly singular kernels more precisely because numerical methods have limitations.
Muna M. Mustafa, Heba A. Abd-Alrazak
doaj   +1 more source

Collocation Solutions of a Weakly Singular Volterra Integral Equation

open access: yesTrends in Computational and Applied Mathematics, 2007
The discrete superconvergence properties of spline collocation solutions for a certain Volterra integral equation with weakly singular kernel are analyzed.
T. Diogo, P. Lima
doaj   +1 more source

Approximate methods for solving degenerate singular integral equations

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Background. Singular integral equations in degenerate cases describe many processes in natural science and technology. The theory of these equations has been studied quite well, but as far as the authors know, there are currently no analytical methods ...
Il'ya V. Boykov, Anastasiya A. Pivkina
doaj   +1 more source

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