Results 41 to 50 of about 2,542,586 (278)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reduction of Boundary Value Problem to Possio Integral Equation in Theoretical Aeroelasticity

Journal of Applied Mathematics, 2008
The present paper is the first in a series of works devoted to the solvability of the Possio singular integral equation. This equation relates the pressure distribution over a typical section of a slender wing in subsonic compressible air flow to the ...
A. V. Balakrishnan, M. A. Shubov
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Singular Higher Order Divergence-Conforming Bases of Additive Kind and Moments Method Applications to 3D Sharp-Wedge Structures [PDF]

, 2008
We present new subsectional, singular divergence conforming vector bases that incorporate the edge conditions for conducting wedges. The bases are of additive kind because obtained by incrementing the regular polynomial vector bases with other ...
GRAGLIA, Roberto, Graglia R.D, Lombardi, Guido   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Mesh-based numerical implementation of the localized boundary-domain integral equation method to a variable-coefficient Neumann problem [PDF]

, 2005
An implementation of the localized boundary-domain integral-equation (LBDIE) method for the numerical solution of the Neumann boundary-value problem for a second-order linear elliptic PDE with variable coefficient is discussed.
Mikhailov, SE, Nakhova, IS
core   +6 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Numerical solution of singular integro-differential Prandtl equation by the method of orthogonal polynomials

Журнал Белорусского государственного университета: Математика, информатика, 2019
The paper is constructed and proved computational scheme for a solution of singular Prandtl of integro-differential  equations with singular integral over the interval of the real axis, understood in the sense of the Cauchy principal value.
Galina A. Rasolko
doaj  

Generalized characteristic singular integral equation with Hilbert kernel [PDF]

Opuscula Mathematica, 2008
In this paper an explicit solution of a generalized singular integral equation with a Hilbert kernel depending on indices of characteristic operators is presented.
Paweł Karczmarek
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source