Results 41 to 50 of about 232,320 (337)

Hamilton-Jacobi quantization of singular Lagrangians with linear velocities

open access: yes, 2004
In this paper, constrained Hamiltonian systems with linear velocities are investigated by using the Hamilton-Jacobi method. We shall consider the integrablity conditions on the equations of motion and the action function as well in order to obtain the ...
A. Corichi   +26 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On Weighted Hadamard-Type Singular Integrals and Their Applications

open access: yesAbstract and Applied Analysis, 2007
By means of an expression with a kind of integral operators, some properties of the weighted Hadamard-type singular integrals are revealed. As applications, the solution for certain strongly singular integral equations is discussed and illustrated.
Yong Jia Xu
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

An Alternative Approach of Initial Stability Analysis of Kirchhoff Plates by the Boundary Element Method

open access: yesEngineering Transactions, 2014
An initial stability of Kirchhoff plates is analysed in the paper. Proposed approach avoids Kirchhoff forces at the plate corner and equivalent shear forces at a plate boundary. Two unknown variables are considered at the boundary element node.
Michał GUMINIAK
doaj   +1 more source

Fast algorithms for Quadrature by Expansion I: Globally valid expansions

open access: yes, 2017
The use of integral equation methods for the efficient numerical solution of PDE boundary value problems requires two main tools: quadrature rules for the evaluation of layer potential integral operators with singular kernels, and fast algorithms for ...
Klöckner, Andreas   +2 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Potential method in the theory of Moore-Gibson-Thompson thermoporoelasticity

open access: yesArchives of Mechanics
In the present paper the linear theory of Moore–Gibson–Thompson thermoporoelasticity is considered and the basic boundary value problems (BVPs) of steady vibrations are investigated.
M. Svanadze
doaj   +1 more source

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