Results 41 to 50 of about 230,153 (288)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Volume and surface integral equations for electromagnetic scattering by a dielectric body

, 2010
13 pagesInternational audienceWe derive and analyze two equivalent integral formulations for the time-harmonic electromagnetic scattering by a dielectric object. One is a volume integral equation (VIE) with a strongly singular kernel and the other one is
Costabel, Martin, Darrigrand, Eric, Koné, El Hadji   +2 more
core   +4 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Boundary Estimate for Singular Parabolic Diffusion Equations

, 2017
We prove an estimate on the modulus of continuity at a boundary point of a cylindrical domain for local weak solutions to singular parabolic equations of p-laplacian type.
Gianazza, Ugo, Liao, Naian, Lukkari, Teemu   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

An Alternative Approach of Initial Stability Analysis of Kirchhoff Plates by the Boundary Element Method

Engineering Transactions, 2014
An initial stability of Kirchhoff plates is analysed in the paper. Proposed approach avoids Kirchhoff forces at the plate corner and equivalent shear forces at a plate boundary. Two unknown variables are considered at the boundary element node.
Michał GUMINIAK
doaj   +1 more source

Hamilton-Jacobi quantization of singular Lagrangians with linear velocities

, 2004
In this paper, constrained Hamiltonian systems with linear velocities are investigated by using the Hamilton-Jacobi method. We shall consider the integrablity conditions on the equations of motion and the action function as well in order to obtain the ...
A. Corichi, D. Baleanu, E. M. Rabei, E. M. Rabei, Eqab M. Rabei, Hosam A. El-Zalan, P. A. M. Dirac, S. A. Hojman, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, S. I. Muslih, Sami I. Muslih, V. Kulshreshtha, Y. Güler, Y. Güler, Y. Güler, Y. Güler   +26 more
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Potential method in the theory of Moore-Gibson-Thompson thermoporoelasticity

Archives of Mechanics
In the present paper the linear theory of Moore–Gibson–Thompson thermoporoelasticity is considered and the basic boundary value problems (BVPs) of steady vibrations are investigated.
M. Svanadze
doaj   +1 more source

On singular solutions of a multidimensional differential equation of Clairaut-type with power and exponential functions

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2019
In the theory of ordinary differential equations, the Clairaut equation is well known. This equation is a non-linear differential equation unresolved with respect to the derivative.
Liliya Leonidovna Ryskina
doaj   +1 more source