Results 71 to 80 of about 1,077,728 (350)
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Relative Perturbation Theory for Hyperbolic Singular Value Problem
We give relative perturbation bounds for singular values and perturbation bounds for singular subspaces of a hyperbolic singular value problem for the pair (G; J), where G is a full rank matrix and J is a diagonal matrix of ...
Ivan Slapnicar +3 more
core +1 more source
Numerical Integration Scheme Using Singular Perturbation Method [PDF]
Some multi degree-of-freedom dynamical systems exhibit a response that contain fast and slow variables. An example of such systems is a multibody system with rigid and deformable bodies. Standard numerical integration of the resultant equations of motion
Parviz E. Nikravesh +5 more
core +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Perturbation Analysis for Robust Damage Detection with Application to Multifunctional Aircraft Structures [PDF]
The most widely known form of multifunctional aircraft structure is smart structures for structural health monitoring (SHM). The aim is to provide automated systems whose purposes are to identify and to characterize possible damage within structures by ...
HAJRYA, Rafik, MECHBAL, Nazih
core
Geometric singular perturbation theory in biological practice [PDF]
Geometric singular perturbation theory is a useful tool in the analysis of problems with a clear separation in time scales. It uses invariant manifolds in phase space in order to understand the global structure of the phase space or to construct orbits ...
Geertje Hek, Hek, G.
core +1 more source
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Free-discontinuity problems generated by singular perturbation
We show that some free discontinuity problems can be obtained as a limit of nonconvex local functionals with a singular perturbation of higher order.
ALICANDRO, Roberto +5 more
core +2 more sources

