Results 51 to 60 of about 1,053,175 (373)

Quasinormal forms for systems of two equations with large delay [PDF]

Известия высших учебных заведений: Прикладная нелинейная динамика
A system of two equations with delay is considered. The purpose of this work is to study the local dynamics of this system under the assumption that the delay parameter is sufficiently large.
Kashchenko, Sergej Aleksandrovich, Tolbey, A. O.   +1 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Singular perturbations and Lindblad-Kossakowski differential equations

, 2008
We consider an ensemble of quantum systems whose average evolution is described by a density matrix, solution of a Lindblad-Kossakowski differential equation.
Mirrahimi, Mazyar, Rouchon, Pierre
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Regular and singular perturbations of upper semicontinuous differential inclusion

International Journal of Mathematics and Mathematical Sciences, 1997
In the paper we study the continuity properties of the solution set of upper semicontinuous differential inclusions in both regularly and singularly perturbed case.
Tzanko Donchev, Vasil Angelov
doaj   +1 more source

Singular limit of an activator-inhibitor type model

Networks and Heterogeneous Media, 2012
We consider a reaction-diffusion system of activator-inhibitor type arising in the theory of phase transition. Itappears in biological contexts such as pattern formation in population genetics.
Marie Henry
doaj   +1 more source

Singular Finsler Double Phase Problems with Nonlinear Boundary Condition

Advanced Nonlinear Studies, 2021
In this paper, we study a singular Finsler double phase problem with a nonlinear boundary condition and perturbations that have a type of critical growth, even on the boundary.
Farkas Csaba, Fiscella Alessio, Winkert Patrick   +2 more
doaj   +1 more source

Combined effects of homogenization and singular perturbations: A bloch wave approach

Networks and Heterogeneous Media, 2021
In this work, we study Bloch wave homogenization of periodically heterogeneous media with fourth order singular perturbations. We recover different homogenization regimes depending on the relative strength of the singular perturbation and length scale of
Vivek Tewary
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Singular Perturbations, Regularization and Extension Theory

, 1994
We present an abstract result on removing regularization for singular potentials which are not semibounded from below. The relation between ``right'' regularizations and ``right'' self-adjoint extensions of the perturbed Schr\"odinger operators is ...
Neidhardt, H., Zagrebnov, V. A.
core   +1 more source