Results 51 to 60 of about 11,648 (307)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Historical developments in singular perturbations [PDF]
, 2014 This engaging text describes the development of singular perturbations, including its history, accumulating literature, and its current status. While the approach of the text is sophisticated, the literature is accessible to a broad audience.
O'Malley, Robert E
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Propagation of singular behavior for Gaussian perturbations of random matrices [PDF]
, 2018 We study the asymptotic behavior of the eigenvalues of Gaussian perturbations of large Hermitian random matrices for which the limiting eigenvalue density vanishes at a singular interior point or vanishes faster than a square root at a singular edge ...
Kuijlaars, Arno +4 more
core +1 more source
Robustness Analysis of a Class of Decentralized Control Systems [PDF]
Modeling, Identification and Control, 1986 The paper presents a method for analysing the robustness properties of a class of decentralized control systems. Perturbations both in local and in interconnection parameters are dealt with. The method is based on the use of singular values.
Ole A. Solheim
doaj +1 more source
Neural networks for singular perturbations
Numerische MathematikAbstract We prove deep neural network (DNN for short) expressivity rate bounds for solution sets of a model class of singularly perturbed, elliptic two-point boundary value problems, in Sobolev norms, on the bounded interval $$(-1,1)$$ (
Joost A. A. Opschoor +2 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Pairs of geometric foliations of regular and singular surfaces [PDF]
, 2010 We examine some generic features of surfaces in the Euclidean 3-space $\mathbb{R}^3$ related to the Gauss map on the surface. We consider these features on smooth surfaces and on singular surfaces with a cross-cap singularity.
Oliver, Joseph Michael +1 more
core
Singular Perturbations of Differential Operators [PDF]
, 2000 Singular perturbations of Schrödinger type operators are of interest in mathematics, e.g. to study spectral phenomena, and in applications of mathematics in various sciences, e.g. in physics, chemistry, biology, and in technology. They also often lead to
Albeverio, Sergio +2 more
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source