Results 131 to 140 of about 592,249 (330)

Unconventional Solution of Singular Integral Equations

open access: yesJournal of Integral Equations and Applications, 1992
The author considers the singular integral equation \[ au(x)+(b/\pi)\int_{-1}^ 1 u(y)(y-x)^{-1} dy+\int_{-1}^ 1 k(x,y)u(y)dy=f(x), \qquad x\in(-1,1),\tag{1} \] where \(a\) and \(b\) are real constants satisfying \(a>0\), \(a^ 2+b^ 2=1\), and the index of equation (1) is \(-1\).
openaire   +3 more sources

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian   +9 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro   +10 more
wiley   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Singular solutions to Protter's problem for the 3-D wave equation involving lower order terms

open access: yesElectronic Journal of Differential Equations, 2003
In 1952, at a conference in New York, Protter formulated some boundary value problems for the wave equation, which are three-dimensional analogues of the Darboux problems (or Cauchy-Goursat problems) on the plane.
Myron K. Grammatikopoulos   +2 more
doaj  

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink   +3 more
wiley   +1 more source

Twin solutions to singular semipositone problems

open access: yesJournal of Mathematical Analysis and Applications, 2003
The author investigates the existence of multiple positive solutions to the following singular semipositone problem: \[ y''+\lambda f(t,y)=0,\quad t\in(0,1),\quad y(0)=y(1)=0, \tag{1\(_\lambda\)} \] where \(\lambda>0\), and \(f(t,y)\) has not necessarily a constant sign and may be singular at \(t=0\), \(t=1\) and \(y=0\).
openaire   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

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