Results 41 to 50 of about 23,140,690 (196)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Pattern Recognition of Gene Expression with Singular Spectrum Analysis

open access: yesMedical Sciences, 2014
Drosophila segmentation as a model organism is one of the most highly studied. Among many maternal segmentation coordinate genes, bicoid protein pattern plays a significant role during Drosophila embryogenesis, since this gradient determines most aspects
Hossein Hassani, Zara Ghodsi
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Balanced Realization and Model Order Reduction for Nonlinear Systems Based on Singular Value Analysis [PDF]

open access: yes, 2004
This paper discusses balanced realization and model order reduction for both continuous-time and discrete-time general nonlinear systems based on singular value analysis of the corresponding Hankel operators.
Fujimoto, Kenji   +6 more
core   +2 more sources

Improved singular spectrum analysis for time series with missing data [PDF]

open access: yesNonlinear Processes in Geophysics, 2015
Singular spectrum analysis (SSA) is a powerful technique for time series analysis. Based on the property that the original time series can be reproduced from its principal components, this contribution develops an improved SSA (ISSA) for processing the ...
Y. Shen, F. Peng, B. Li
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Peramalan curah hujan di kota bandung menggunakan singular spectrum analysis [PDF]

open access: yes, 2021
Curah hujan merupakan fenomena alam yang selalu terjadi di Indonesia setiap tahunnya. Fenomena ini bisa saja menyebabkan bencana seperti banjir dan tanah longsor. Adanya peramalan sangat dibutuhkan sebagai bentuk peringatan dini mengenai kondisi di waktu
Febrianti, Tri Kartika   +2 more
core   +1 more source

Filtering of digital terrain models by 2D Singular Spectrum Analysis

open access: yes, 2007
Singular Spectrum Analysis (SSA) has been approved as a model-free technique to analyse time series. SSA can solve different problems such as decomposition into a sum of trend, periodicities, and noise, smoothing, and others.
Usevich, Konstantin   +2 more
core   +1 more source

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