Results 51 to 60 of about 1,040,227 (270)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On the spectrum of noisy blown-up matrices
We study the eigenvalues of large perturbed matrices. We consider a pattern matrix P, we blow it up to get a large block-matrix Bn. We can observe only a noisy version of matrix Bn. So we add a random noise Wn to obtain the perturbed matrix An = Bn + Wn.
Fazekas István, Pecsora Sándor
doaj +1 more source
THE SMALLEST SINGULAR VALUE OF INHOMOGENEOUS SQUARE RANDOM MATRICES [PDF]
We show that for an $n\times n$ random matrix $A$ with independent uniformly anti-concentrated entries, such that $\mathbb{E} ||A||^2_{HS}\leq K n^2$, the smallest singular value $\sigma_n(A)$ of $A$ satisfies $$ P\left( \sigma_n(A)\leq \frac{\varepsilon}
Livshyts, Galyna V +2 more
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Robust Image Watermarking in Spatial Domain Utilizing Features Equivalent to SVD Transform
In recent years, digital image watermarking has gained a significant amount of popularity and developed into a crucial and essential tool for copyright protection, security, and the identification of multimedia content.
Musrrat Ali
doaj +1 more source
Guaranteed Rank Minimization via Singular Value Projection [PDF]
Minimizing the rank of a matrix subject to affine constraints is a fundamental problem with many important applications in machine learning and statistics.
Dhillon, Inderjit S. +2 more
core +2 more sources
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Improved singular value inclusion sets for rectangular tensors
In this paper, improved singular value inclusion sets for rectangular tensors are given, which are tighter than those in (Zhao and Li in Linear Multilinear Algebra 66(7):1333–1350, 2018).
Jun He, Yanmin Liu
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

