Results 61 to 70 of about 6,019,459 (297)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Generalized Singular Value Thresholding

Proceedings of the AAAI Conference on Artificial Intelligence, 2015
This work studies the Generalized Singular Value Thresholding (GSVT) operator associated with a nonconvex function g defined on the singular values of X. We prove that GSVT can be obtained by performing the proximal operator of g on the singular values since Proxg(.) is monotone when g is lower bounded. If the nonconvex g satisfies some
Canyi Lu, Changbo Zhu, Chunyan Xu, Shuicheng Yan, Zhouchen Lin   +4 more
openaire   +4 more sources

Least Squares Estimation of PSI Networks for Large Scenes with Multithreaded Singular Value Decomposition [PDF]

, 2010
In the Persistent Scatterer Interferometry relative height and deformation updates are estimated between nearby persistent scatterers (PSs). In practice, a reference network is established and the absolute values are estimated by integration.
Parizzi, Alessandro, Liebhart, Werner, Adam, Nico Alexander   +2 more
core  

Characteristics and Detection Algorithm of Strong and Weak Arc in Low Voltage DC Distribution Network

Zhongguo dianli
With no zero-crossing characteristic, DC arc is difficult to extinguish by itself, and is inclined to cause electrical fire, threatening the safety of DC power distribution.
Guoqiang LIU, Guochun LI, Yanan HAO, Guihai LI, Zhongjie WU   +4 more
doaj   +1 more source

Robust Image Watermarking in Spatial Domain Utilizing Features Equivalent to SVD Transform

Applied Sciences, 2023
In recent years, digital image watermarking has gained a significant amount of popularity and developed into a crucial and essential tool for copyright protection, security, and the identification of multimedia content.
Musrrat Ali
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Singular random matrix decompositions: distributions. [PDF]

, 2002
Assuming that Y has a singular matrix variate elliptically contoured distribution with respect to the Hausdorff measure, the distributions of several matrices associated to QR, modified QR, SV and Polar decompositions of matrix Y are determined, for ...
González Farías, Graciela, Díaz García, José A., José A. Díaz-garcía, Graciela González-farías   +3 more
core   +1 more source

Localized boundary-domain singular integral equations based on harmonic parametrix for divergence-form elliptic PDEs with variable matrix coefficients [PDF]

, 2013
This is the post-print version of the Article. The official publised version can be accessed from the links below. Copyright @ 2013 Springer BaselEmploying the localized integral potentials associated with the Laplace operator, the Dirichlet, Neumann and
Mikhailov, SE, Natroshvili, D, Chkadua, O   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source