Results 21 to 30 of about 1,935 (167)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Computing μ-Values for Real and Mixed μ Problems

open access: yesMathematics, 2019
In various modern linear control systems, a common practice is to make use of control in the feedback loops which act as an important tool for linear feedback systems.
Mutti-Ur Rehman   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Characteristic gene selection via weighting principal components by singular values. [PDF]

open access: yesPLoS ONE, 2012
Conventional gene selection methods based on principal component analysis (PCA) use only the first principal component (PC) of PCA or sparse PCA to select characteristic genes.
Jin-Xing Liu   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Highlighting Link Prediction in Bipartite Networks via Structural Perturbation

open access: yesIEEE Access, 2018
Most of the link prediction algorithms for bipartite networks assume that the generation of link is based on a predefined prior assumption. However, for the real-world bipartite networks, the generation mechanism of link is still ambiguous due to their ...
Xue Chen   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Análise de Espectro Singular e Wavelet sobre Série Temporal de Profundidade Ótica de Aerossóis no Pantanal do Brasil

open access: yesRevista Brasileira de Meteorologia
Resumo As variações das propriedades óticas dos aerossóis podem interferir nos processos de transferência de energia entre a atmosfera e a superfície terrestre. A AOD (Aerosol Optical Depth) é a variável mais usada para este propósito, a qual possibilita
Rafael da Silva Palácios   +7 more
doaj   +1 more source

Development of a Method for Selection of Effective Singular Values in Bearing Fault Signal De-Noising

open access: yesApplied Sciences, 2016
Singular value decomposition (SVD) is a widely used and powerful tool for signal extraction under noise. Noise attenuation relies on the selection of the effective singular value because these values are significant features of the useful signal ...
Jie Gao   +3 more
doaj   +1 more source

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