Results 71 to 80 of about 917,126 (263)

Block Power Method for SVD Decomposition

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
We present in this paper a new method to determine the k largest singular values and their corresponding singular vectors for real rectangular matrices A ∈ Rn×m.
Bentbib A. H., Kanber A.
doaj   +1 more source

V-singular values of rectangular tensors and their applications

open access: yesJournal of Inequalities and Applications, 2019
The positive definiteness of rectangular tensors has wide applications in solid mechanics and quantum physics. By modifying the existing definition of singular value for rectangular tensors, some V-singular value inclusion sets for rectangular tensors ...
Jun He   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Componentwise Perturbation Analysis of the Singular Value Decomposition of a Matrix

open access: yesApplied Sciences
A rigorous perturbation analysis is presented for the singular value decomposition (SVD) of a real matrix with full column rank. It is proved that the SVD perturbation problem is well posed only when the singular values are distinct.
Vera Angelova, Petko Petkov
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Research on rolling bearing fault diagnosis technology based on singular value decomposition

open access: yesAIP Advances
To solve the difficulty of selecting the number of effective singular values in Singular Value Decomposition denoising, a new method to determine the number of effective singular values is proposed.
Jingfang Ji, Jingmin Ge
doaj   +1 more source

A Note on Inclusion Intervals of Matrix Singular Values

open access: yesJournal of Applied Mathematics, 2012
We establish an inclusion relation between two known inclusion intervals of matrix singular values in some special case. In addition, based on the use of positive scale vectors, a known inclusion interval of matrix singular values is also improved.
Shu-Yu Cui, Gui-Xian Tian
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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