Results 51 to 60 of about 1,222,032 (295)
Non-linear forcing singular vector of a two-dimensional quasi-geostrophic model [PDF]
Tellus: Series A, Dynamic Meteorology and Oceanography, 2013 We propose a non-linear forcing singular vector (NFSV) approach to infer the effect of non-linearity on the predictability associated with model errors. The NFSV is a generalisation of the forcing singular vector (FSV) to non-linear fields and acts as a ...
Wansuo Duan, Feifan Zhou
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Singular vectors of orthogonally decomposable tensors [PDF]
Linear and Multilinear Algebra, 2017 Orthogonal decomposition of tensors is a generalization of the singular value decomposition of matrices. In this paper, we study the spectral theory of orthogonally decomposable tensors. For such a tensor, we give a description of its singular vector tuples as a variety in a product of projective spaces.
Robeva, E, Seigal, A
openaire +3 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Implementation of Higher-Order Two-Dimensional Singular Elements in FEM codes and Numerical Results problems [PDF]
, 2003 This paper presents strategies and schemes to implement higher-order two dimensional singular elements in Finite Elements codes.
Lombardi, Guido
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Art of Singular Vectors and Universal Adversarial Perturbations [PDF]
2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, 2018 Submitted to CVPR ...
Valentin Khrulkov, Ivan V. Oseledets
openaire +4 more sources