Results 81 to 90 of about 13,466 (269)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Singularities of Type-Q ABS Equations
Symmetry, Integrability and Geometry: Methods and Applications, 2011 The type-Q equations lie on the top level of the hierarchy introduced by Adler, Bobenko and Suris (ABS) in their classification of discrete counterparts of KdV-type integrable partial differential equations.
James Atkinson
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Singular LQ Problem for Irregular Singular Systems
Journal of Applied Mathematics, 2014 This paper is concerned with the singular LQ problem for irregular singular systems with persistent disturbances. The full information feedback control method is employed to achieve the optimal control. By restricted system equivalence transformation, the system state is decomposed into free state and restricted state and the input is decomposed into ...
Qingxiang Fang +2 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Demonstratio MathematicaIn this study, singularity theory is used to explore the geometrical and topological properties of three types of curves and surfaces in multiplicative Euclidean space.
Li Jiaxin +3 more
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IEEE Access, 2020 The formulations for three-dimensional (3D) scattering from uniaxial objects with a smooth boundary using a multiple infinitesimal dipole method (MIDM) are introduced.
Kai Wang +4 more
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
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Transactions of the American Mathematical Society, 1991 The main result of this paper is a characterization of singular cardinals in terms of the core model, assuming that there is no model of ∃
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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