Results 71 to 80 of about 23,028 (249)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

A Singular Functional [PDF]

Proceedings of the American Mathematical Society, 1956
in which the functions r, p and q are continuous on (0, oo) while r is positive there. The point x=O is singular for the functional in the sense that the conditions on r, p, and q may not hold for an interval of the form [0, b]. Finally, all integrals which appear are Lebesgue integrals.
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A 3UPS/S Spherical Parallel Manipulator Designed for Robot-Assisted Hand Rehabilitation after Stroke

Applied Sciences
Hand dysfunction is a common symptom in stroke patients. This paper presents a robotic device which assists the rehabilitation process in order to reduce the need of physical therapy, i.e., a 3UPS/S parallel robotic device is employed for repetitive ...
Tony Punnoose Valayil, Tanio K. Tanev
doaj   +1 more source

ACCOMPANIEMENT FOR NEWLY RECRUITED TEACHERS IN THE POST-PANDEMIC CLASSROOM: EXPERIENCE, TEMPORALITY, COMPLEXITY & SINGULARITY [PDF]

Analele Universităţii din Craiova. Psihologie, Pedagogie
Remote support training for newly recruited university teachers has been adopted by the supervisory authority in Algeria during the post-pandemic period.
Mounir MILOUDI
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

On the SVMpath Singularity

IEEE Transactions on Neural Networks and Learning Systems, 2013
This paper proposes a novel ridge-adding-based approach for handling singularities that are frequently encountered in the powerful SVMpath algorithm. Unlike the existing method that performs linear programming as an additional step to track the optimality condition path in a multidimensional feasible space, our new approach provides a simpler and ...
Jisheng, Dai, Chunqi, Chang, Fei, Mai, Dean, Zhao, Weichao, Xu   +4 more
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Identifying alterations of Zafarghand porphyry copper system (Isfahan): employing singularity method and false color composite [PDF]

International Journal of Mining and Geo-Engineering
In recent times, geological remote sensing has greatly enhanced the ability to access alteration zones and identify potential sites for hydrothermal deposits quickly and cost-effectively.
Seyyed saeed Ghannadpour, Morteza Hasiri, Hadi Jalili, Hamid Salehi Shahrabi   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source