Results 61 to 70 of about 244,947 (267)

sylabs/singularity: SingularityCE 4.0.0

open access: yes, 2023
We are pleased to announce the availability of SingularityCE 4.0.0. This is a new major version, with the new OCI-mode becoming fully supported and expanded to use OCI-SIF images.
Dave Trudgian   +27 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Finite-time singularity formation at a magnetic neutral line in Hall magnetohydrodynamics [PDF]

open access: yes, 2015
The formation of a current sheet in a weakly collisional plasma can be modelled as a finite-time singularity solution of magnetohydrodynamic equations.
Litvinenko, Yuri E.   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A study on performance degradation when using Singularity container of HTCondor scheduler

open access: yes, 2022
It is very simple for users to use HTCondor's Singularity container. HTCondor's built-in Singularity Container was used to perform CPU intensive tasks. To use the test result, the pipeline of HTCondor and Singularity was investigated how much performance
류건모   +3 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

AI AND THE SINGULARITY

open access: yes, 2020
"AI and the Technological Singularity: A Fallacy or a Great Opportunity" is a collection of essays that addresses the question of whether the technological singularity—the notion that AI-based computers can program the next generation of AI-based ...

core   +1 more source

Evanescent Electron Wave-Spin

open access: yesEntropy
This study demonstrates the existence of an evanescent electron wave outside both finite and infinite quantum wells by solving the Dirac equation and ensuring the continuity of the spinor wavefunction at the boundaries.
Ju Gao, Fang Shen
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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