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The surgical anatomy of the sinoatrial node
Surgical and Radiologic Anatomy, 1991The sinoatrial nodes (SAN) were observed, dissected, and measured on 95 adults and 30 child hearts under a dissection microscope. The majority of the SANs in adults are characterized by their pale color, firm consistency, and the location in relation to the penetration of the SAN artery, and they can be located in the superior part of the terminal ...
B M, He, Y X, Tan, M, Cheng, Y Q, Cui
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STRUCTURE-FUNCTION RELATIONSHIPS OF THE SINOATRIAL NODE
International Journal of Bifurcation and Chaos, 2003The sinoatrial node, the pacemaker of the heart, is a structurally and functionally complex and heterogeneous structure. Histology, immunohistochemistry, electrophysiology and mathematical modeling of the sinoatrial node are reviewed to reveal the structure-function relationships of the sinoatrial node. It is argued that contact between the sinoatrial
Dobrzynski, Halina +4 more
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Journal of Molecular and Cellular Cardiology, 1985
The primary pacemaker, i.e. the group of pacemaker cells discharging the sinoatrial node comprises less than 1000 cells in the guinea-pig and about 5000 cells in the rabbit. These primary pacemaker cells are described as 'central nodal' cells in light microscopy and as 'typical nodal' cells in electron microscopy.
T, Opthof +6 more
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The primary pacemaker, i.e. the group of pacemaker cells discharging the sinoatrial node comprises less than 1000 cells in the guinea-pig and about 5000 cells in the rabbit. These primary pacemaker cells are described as 'central nodal' cells in light microscopy and as 'typical nodal' cells in electron microscopy.
T, Opthof +6 more
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Isolation of sinoatrial node cells
1993Abstract The dissociation of cardiac tissue into single cells opened up new possibilities for physiological investigation which have led in the last decade to major advances in knowledge of heart function at the cellular level. Cardiac cell isolation was pioneered in the 1970s (1) and was quickly adopted by many other groups.
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If and sinoatrial node pacemaking
2004The majority of Na+ channels in the heart are composed of the tetrodotoxin (TTX)-resistant (KD, 2-6 μM) Nav1.5 isoform; however, recently it has been shown that TTX-sensitive (KD, 1-10 nM) neuronal Na+ channel isoforms (Nav1.1, Nav1.3 and Nav1.6) are also present and functionally important in the myocytes of the ventricles and the sinoatrial (SA) node.
A. Bucchi, M. Baruscotti, D. DiFrancesco
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