Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu +5 more
wiley +1 more source
Fermentation method outweighs geographic origin in shaping kefir's <i>in vitro</i> anti-obesity potential and probiotic properties. [PDF]
Ji Q, Qu H, Li Q, Gu R.
europepmc +1 more source
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang +15 more
wiley +1 more source
Core-shell structured magnetic γ-Fe<sub>2</sub>O<sub>3</sub>@Cu-La composite material for enhanced arsenic removal: Behavior and mechanism. [PDF]
Zhang W +7 more
europepmc +1 more source
Synergistic CuMoP Nanocomposite‐Modified Carbon Electrode for Ultrasensitive Detection of Aspirin
A CuMoP ternary system‐modified screen‐printed carbon electrode is developed via a one‐step electrodeposition strategy for the electrochemical detection of aspirin. The synergistic Cu–Mo–P redox network promotes efficient electron–proton coupling, enabling reliable and reproducible sensing.
Hong Wan +5 more
wiley +1 more source
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Qualitative exploration of COVID-19 vaccine uptake among healthcare workers in Sierra Leone: do the 'trusted messengers' trust the vaccine? [PDF]
David I, Schatz E, Majee W.
europepmc +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
The First Case of Linear Cutaneous Lupus Erythematosus Following Covid-19 Vaccination: A Case Report. [PDF]
Saberi F +5 more
europepmc +1 more source
An Implanted Tooth That Can Feel
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao +13 more
wiley +1 more source

