Results 51 to 60 of about 352,828 (288)

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Biological Principles and Physiology of Bone Regeneration under the Schneiderian Membrane after Sinus Lift Surgery: A Radiological Study in 14 Patients Treated with the Transcrestal Hydrodynamic Ultrasonic Cavitational Sinus Lift (Intralift)

International Journal of Dentistry, 2012
Introduction. Sinus lift procedures are a commonly accepted method of bone augmentation in the lateral maxilla with clinically good results. Nevertheless the role of the Schneiderian membrane in the bone-reformation process is discussed controversially ...
A. Troedhan, A. Kurrek, M. Wainwright
doaj   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Optimized beagle model for maxillary sinus floor augmentation via a mini-lateral window with simultaneous implant placement

Journal of International Medical Research, 2018
Objective This study was performed to establish an optimized beagle model for maxillary sinus floor augmentation via a mini-lateral window with simultaneous implant placement. Methods Twelve beagles underwent maxillary sinus floor augmentation via a mini-
Liqin Zhu, Jiakang Yang, Jiaxing Gong, Chenqiu Zhang, Huiming Wang   +4 more
doaj   +1 more source

Sinus floor augmentation using mixture of mineralized cortical bone and cancellous bone allografts: Radiographic and histomorphometric evaluation

Journal of Dental Sciences, 2020
Background/purpose: Due to the pneumatization of the maxillary sinus, the sinus floor augmentation is often performed to implant placement in the maxillary posterior region.
Hyun-Woo Kim, Kyeong-Ok Lim, Won-Pyo Lee, Yo-Seob Seo, Hong-In Shin, Seong-Ho Choi, Byung-Ock Kim, Sang-Joun Yu   +7 more
doaj   +1 more source

CLINICAL AND RADIOLOGICAL FEATURES OF THE MAXILLARY SINUS IN PATIENTS AFTER REMOVAL OF FUNGAL BALL AND THEIR IMPACT ON THE FREQUENCY OF SUBANTRAL BONE AUGMENTATION COMPLICATIONS.

Клінічна та профілактична медицина, 2021
. The mucoperiostitis and local osteitis are radiological symptoms of the fungal ball of the maxillary sinuses. The condition of the mucoperiosteum and the adjacent bone in the alveolar bay of the maxillary sinus predict the results of dental ...
Ya.V. Shkorbotun
doaj   +1 more source

Minimally Invasive Sinus Augmentation: A Systematic Review. [PDF]

Clin Implant Dent Relat Res
ABSTRACT Aim Technology improvement and a better understanding of sinus anatomy and wound healing in the past decade have allowed the development of minimally invasive surgical techniques. This systematic review focused on identifying and describing these techniques for vertical and lateral ...
Sirinirund B, Rodriguez Betancourt AB, Scaini R, Wu YC, Chan HL.   +4 more
europepmc   +3 more sources

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Comparative Evaluation of AI-Assisted and Manual CBCT-Derived Graft Volume Measurements for Maxillary Sinus Floor Augmentation

Diagnostics
Background/Objectives: Accurate estimation of augmentation volume is essential for successful maxillary sinus augmentation planning. Manual CBCT-derived volumetric calculations remain time-consuming and operator-dependent.
Badr Othman
doaj   +1 more source

Endoscopically monitored maxillary sinus augmentation - The chairside approach (Rationale and protocol)

Journal of Oral Biology and Craniofacial Research, 2020
Sinus augmentation procedures have been reported since the time of Boyne, with variable techniques and outcomes.Sinus membrane perforations may or may not be detected at the intra-operative stage, thereby compromising the outcome.The aim of this study is
Yazad Gandhi
doaj   +1 more source