Results 51 to 60 of about 44,700 (293)

The role of inhibitory G proteins and regulators of G protein signaling in the in vivo control of heart rate and predisposition to cardiac arrhythmias [PDF]

, 2012
Inhibitory heterotrimeric G proteins and the control of heart rate. The activation of cell signaling pathways involving inhibitory heterotrimeric G proteins acts to slow the heart rate via modulation of ion channels.
Ang, R, Opel, A, Tinker, A
core   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Carotid sinus hypersensitivity: Entity warrants a caution in the critical care unit

Journal of the Scientific Society, 2016
Carotid sinus hypersensitivity (CSH) syndrome is an entity caused by an overreaction of the carotid sinus baroreceptors to stimulation. Three subtypes of CSH syndrome are recognized according to the response to carotid sinus massage (CSM): Predominantly ...
Sugata Dasgupta, Soumi Das, Arunima Chaudhuri   +2 more
doaj   +1 more source

Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa, Jessica R. Landers, Nicholas S. Abend, Giulia M. Benedetti, Catherine J. Chu, Andrew T. Knox, Shavonne Massey, Steffany Moen, Andrea C. Pardo, Arnold Sansevere, Renée A. Shellhaas, Cameron Thomas, Tammy Tsuchida, Sonya Wang, Bo Zhang, Janet S. Soul   +15 more
wiley   +1 more source

International criteria for electrocardiographic interpretation in athletes: Consensus statement. [PDF]

, 2017
Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A variety of mostly hereditary, structural or electrical cardiac disorders are associated with SCD in young athletes, the majority of which can be identified or ...
Aagaard, Aaron Baggish, Ackerman, Anderson, Andre La Gerche, Antonio Pelliccia, Antzelevitch, Aro, Asif, Baggish, Bakken, Basavarajaiah, Bayés de Luna, Bazett, Behr, Bent, Bent, Bessem, Biffi, Biffi, Bjørnstad, Borjesson, Brosnan, Brosnan, Brosnan, Brosnan, Calore, Calore, Calò, Carmen Adamuz, Chad A Asplund, Chandra, Chen, Chou, Christian M Schmied, Chung, Chung, Cohen, Corrado, Corrado, Corrado, Corrado, Corrado, Daubert, David M Shipon, David S Owens, Daviglus, Delise, Delise, Desai, Dhutia, Di Paolo, Domenico Corrado, Drezner, Drezner, Drezner, Drezner, Drezner, Drezner, Drezner, Dunn, Eckart, Elliott, Eugene H Chung, Exeter, Finocchiaro, Fudge, Gati, Goldenberg, Gollob, Gordon Cohen, Groh, Haghjoo, Hancock, Hank F Pelto, Harmon, Harmon, Haïssaguerre, Heidbuchel, Heidbüchel, Hein Heidbuchel, Hill, Huston, Irfan M Asif, Jack C Salerno, James, Johnson, Johnson, Jonathan A Drezner, Jordan M Prutkin, Josef Niebauer, Joseph C Marek, Junttila, Kapplinger, Kim, Kim, Kimberly G Harmon, Klein, Klein, La Gerche, Lakdawala, Le, Link, MacAlpin, Macfarlane, Magalski, Magee, Malfatto, Malhotra, Marco V Perez, Marcus, Marek, Maron, Maron, Maron, Maron, Maron, Maron, Mason, Mathew G Wilson, Mats Borjesson, Meyer, Meytes, Michael J Ackerman, Michael Papadakis, Michael S Emery, Migliore, Nasir, Nathan R Riding, Northcote, Noseworthy, Noseworthy, Novak, Papadakis, Papadakis, Pelliccia, Pelliccia, Pelliccia, Pickham, Platonov, Postema, Price, Prior, Priori, Quattrini, Ranthe, Ranthe, Rautaharju, Rawlins, Ricardo Stein, Riding, Riding, Rose, Rosso, Rowin, Ruwald, Ryan, Saguner, Sahlén, Sanjay Sharma, Sathanandam, Sawant, Schnell, Schwartz, Schwartz, Schwartz, Sharma, Sheikh, Sheikh, Sheikh, Silvana Molossi, Sohaib, Stein, Surawicz, Taggart, Takken, Tan, Tess Saarel, Tester, Tester, Tester, Tikkanen, Tikkanen, Uberoi, Uberoi, Uhm, Verdile, Victor F Froelicher, Victoria L Vetter, Vincent, Viskin, Wasfy, Weiner, Wilde, Williams, Wilson, Xiao, Zaidi, Zorzi   +198 more
core   +2 more sources

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy [PDF]

, 2019
Investigation of marine mammal dive-by-dive blood distribution and oxygenation has been limited by a lack of non-invasive technology for use in freely diving animals.
Balfour, Steve, Bennett, Kimberley A., Bivins, Matt, Bronkhorst, Mathijs, Colier, Willy, Hall, Ailsa J., McKnight, J. Chris, Milne, Ryan, Moss, Simon E. W., Russell, Debbie J. F., Thompson, Dave   +10 more
core   +4 more sources

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Beta-Blocker-Related Atrioventricular Conduction Disorders—A Single Tertiary Referral Center Experience

Medicina, 2022
Background and Objectives: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions.
Dragoș Traian Marius Marcu, Cristina Andreea Adam, Dan-Mihai Dorobanțu, Delia Lidia Șalaru, Radu Andy Sascău, Mircea Ovanez Balasanian, Liviu Macovei, Cătălina Arsenescu-Georgescu, Cristian Stătescu   +8 more
doaj   +1 more source

Cardiovascular morbidity following epilepsy: A nationwide retrospective cohort study in South Korea

Epilepsia Open, EarlyView.
Abstract Objective This study evaluated the long‐term risk of major cardiovascular diseases (CVDs) in patients with epilepsy using a nationwide cohort, aiming to address critical gaps in population‐based evidence on brain–heart interactions. Methods Data from the Korean National Health Insurance Service (2002–2013) were analyzed.
Youngoh Bae, Chaeyoon Kang, Yejin Lee, Haerim Cho, Hohyun Jung, Seung Won Lee   +5 more
wiley   +1 more source