Results 71 to 80 of about 142,538 (247)

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Bradyarrhythmias secondary to topical levobunolol hydrochloride solution

Clinical Interventions in Aging, 2014
Lianjun Lin,* Yuchuan Wang,* Yan Chen, Meilin Liu Geriatric Department, Peking University First Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: An 88-year-old man was admitted with fatigue,
Lin LJ, Wang YC, Chen Y, Liu ML
doaj  

Sinus Bradycardia after Extensive Neck Dissection and Total Thyroidectomy in a Pediatric Patient: A Case Report

The Surgery Journal, 2020
Postoperative complications after total thyroidectomy with extensive neck dissection in thyroid malignancies are well documented in the current literature.
Antonia Malli, Ioannis Skondras, Maria Vakaki, Alexander Passalides   +3 more
doaj   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Sisplatin İnfüzyonuna Bağlı Tekrarlayan Bradikardi Atakları

Sakarya Tıp Dergisi, 2013
Chemotherapy may induce entire spectrum of cardiac pathology. Cisplatin has been used in oncology practice for a long time, but no sufficient clinical evidence exists about arrhythmogenic potential of this drug.
Ali Tamer, Devrim Çabuk, Mehmet Bülent Vatan, Mustafa Volkan Demir, Selçuk Yaylacı   +4 more
doaj   +1 more source

Long QT syndrome in neonates Conduction disorders associated with HERGmutations and sinus bradycardia with KCNQ1mutations [PDF]

, 2004
ObjectivesWe hypothesized that neonatal long QT syndrome (LQTS) with 2:1 atrioventricular block (AVB) could be related to HERGmutations.BackgroundEarly onset of LQTS is rare but carries a high risk of life-threatening events such as ventricular ...
Lupoglazoff, Jean-Marc, Denjoy, Isabelle, Villain, Elisabeth, Simon, Françoise, Hainque, Bernard, Guicheney, Pascale, Berthet, Myriam, Bozio, André, Benammar, Nawal, Fressart, Véronique   +9 more
core   +1 more source

Impact of Ganglionated Plexus Ablation on Early Recurrence After Thoracoscopic Atrial Fibrillation Ablation: A Post Hoc Analysis of the AFACT Study

Journal of Cardiovascular Electrophysiology, EarlyView.
Adjunctive ganglionated plexus (GP) ablation did not reduce early AF recurrence after thoracoscopic AF ablation but was associated with a later first recurrence. In the GP‐ablation group, early recurrence was associated with late recurrence; this exploratory finding is compatible with, but does not establish, a greater contribution of pre‐existing ...
Zhenyu Dong, Marc M. Terpstra, Jolien Neefs, Nicoline W.E. van den Berg, Femke R. Piersma, Sebastien P.J. Krul, Wouter R. Berger, Wim‐Jan P. van Boven, Jonas S.S.G. de Jong, Ruben Coronel, Joris R. de Groot, Antoine H.G. Driessen   +11 more
wiley   +1 more source

CONTRIBUTION OF AUTONOMIC NERVOUS SYSTEM EXPLORATION IN THE DIAGNOSIS OF SYMPTOMATIC SINUS BRADYCARDIA-A REPORT OF TWO CASES.

, 2019
A symptomatic sinus bradycardia is a very common situation in cardiology for which the diagnostic and therapeutic management are far from being well codified.
Roukia Fellat, Mohamed Cherti., Salwa Cheraou, Ilyas El-Kassimi, Amine Ahmindach, Lalla Fatima Ezzahra El-Hassani, Halima Benjelloun   +6 more
core   +1 more source

Refractory bradycardia – a rare complication of carboprost tromethamine for induction of abortion

Acta Clinica Croatica, 2016
We report a first case of refractory several-hour sinus bradycardia, a rare but already described side effect of intramuscular administration of carboprost tromethamine to induce abortion for medical indication in a patient without cardiovascular and ...
Jasna Čerkez Habek, Dubravko Habek, Dario Gulin   +2 more
doaj   +1 more source