Results 91 to 100 of about 115,003 (193)
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon +3 more
wiley +1 more source
Juvenile dermatomyositis with a rare and remarkable complication: sinus bradycardia
Juvenile dermatomyositis (JDM) is characterized by proximal muscle weakness, vasculopathy of the skin and muscles, and typical skin rash. Approximately, 70% of adult patients with dermatomyositis have evidence of cardiac damage.
Kutukculer, Necil +3 more
core +1 more source
Heart rate changes during partial seizures: A study amongst Singaporean patients
Introduction Studies in Europe and America showed that tachycardia, less often bradycardia, frequently accompanied partial seizures in Caucasian patients.
Lim Shih-Hui, Wilder-Smith Einar
doaj +1 more source
ABSTRACT Background Leadless pacemakers traditionally rely on femoral venous access, which may be limited in patients with unfavorable IVC anatomy, prior interventions, or situations where preserving femoral access is preferred. Internal jugular (IJ) access offers an alternative route, but real‐world data on IJ implantation of single‐ and dual‐chamber ...
Maya Asami Takagi +3 more
wiley +1 more source
Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Asymptomatic Profound Sinus Bradycardia (Heart Rate ≤45) in Non-small Cell Lung Cancer Patients Treated with Crizotinib [PDF]
:Crizotinib, a dual MET/ALK inhibitor, is now in advanced clinical development for the treatment of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC).
Joni Dy +7 more
core +1 more source
Focal atrial tachycardia (AT) is sometimes associated with sick sinus syndrome. A 57-year-old female complained of palpitation, fatigue and presyncope. Ambulatory monitoring demonstrated frequent segments of AT and subsequent sinus arrests.
Shioto Yasuda, MD +9 more
doaj +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Transient sinus bradycardia during the course of Crimean-Congo hemorrhagic fever in children
Crimean-Congo hemorrhagic fever (CCHF) is an acute tick-borne viral zoonotic disease which is endemic in Turkey. Bradycardia has been reported among pediatric and adult patients with CCHF.
Metin, Ozge +7 more
core +1 more source

