Results 101 to 110 of about 19,247 (255)

Mechanism of Sinus Node Dysfunction in Carriers of the E161K Mutation in the SCN5A Gene

, 2018
Heterozygous carriers of the E161K mutation in the SCN5A gene, which encodes the NaV1.5 pore-forming α-subunit of the ion channel carrying the cardiac fast sodium current (INa), show sinus node dysfunction.
Wilders, Ronald, Ronald Wilders
core   +2 more sources

Permanent and temporary pacemaker implantation after orthotopic heart transplantation

Arquivos Brasileiros de Cardiologia, 2000
PURPOSE:To determine the indication for and incidence and evolution of temporary and permanent pacemaker implantation in cardiac transplant recipients. METHODS: A retrospective review of 114 patients who underwent orthotopic heart transplantation InCor ...
Bacal Fernando, Bocchi Edimar A., Vieira Marcelo L. C., Lopes Neusa, Moreira Luiz Felipe, Fiorelli Alfredo, Costa Roberto, Martinelli Martino, Stolf Noedir A. G., Bellotti Giovanni, Ramires José Antonio F.   +10 more
doaj  

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Real‐World Treatment of Patients With Sinus Node Dysfunction and Heart Failure With Preserved Ejection Fraction

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Permanent pacemaker (PPM) implantation is recommended in patients with sinus node dysfunction (SND). In patients with coexisting heart failure with preserved ejection fraction (HFpEF), clinicians may be hesitant to treat SND due to concerns about exacerbating heart failure.
Nicole Habel, Sarah Rosemas, Lucas Higuera, Patrick Zimmerman, Markus Meyer   +4 more
wiley   +1 more source

Incidental Arrhythmias During Atrial Fibrillation Screening With Repeat 7‐Day Holter ECGs in a Hospital‐Based Patient Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Screening for atrial fibrillation (AF) may reveal incidental arrhythmias of relevance. The aim of this study was to describe incidental arrhythmias detected during screening for AF in the STAR‐FIB (Predicting SilenT AtRial FIBrillation in ...
Eleni Goulouti, Anna Lam, Nikolas Nozica, Elena Elchinova, Chrisoula Dernektsi, Felix Neugebauer, Mattia Branca, Helge Servatius, Fabian Noti, Andreas Haeberlin, Gregor Thalmann, Nikola Asenov Kozhuharov, Antonio Madaffari, Hildegard Tanner, Tobias Reichlin, Laurent Roten   +15 more
doaj   +1 more source

Syncope due to sinus node dysfunction after surgical patch closure of atrial septal defect: A case report

, 2017
Introduction. Sick sinus syndrome, a frequent cause of syncope, refers to a combination of symptoms caused by sinus node dysfunction. Case report.
Larisa Dizdarevic-Hudic, Zumreta Kusljugic, Igor Hudic, Irma Bijedic   +3 more
core   +1 more source

Impact of Leadless Pacemaker Implantation Position on Subclinical Right Ventricular Perforation

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Leadless pacemakers are typically implanted in the mid‐septum of the right ventricle (RV) to mitigate the risk of perforation. However, reports on the precise location of these implants are limited. This study aimed to elucidate tine‐based leadless pacemaker position and presence of subclinical RV perforation through computed ...
Young Shin Lee, Jae‐Sun Uhm, Je‐Wook Park, Seung‐Jung Park, Ye Chan Kim, In‐Soo Kim, Hye‐Jeong Lee, Moon‐Hyun Kim, Hanjin Park, Daehoon Kim, Hee Tae Yu, Tae‐Hoon Kim, Jin‐Bae Kim, Jong‐Youn Kim, Boyoung Joung, Hui‐Nam Pak, Moon‐Hyoung Lee   +16 more
wiley   +1 more source

QT Interval Evaluation in Right Ventricular Pacing: Validation of a Novel Formula

Pacing and Clinical Electrophysiology, EarlyView.
Abstract Background QT interval measurement in the presence of right ventricular pacing (RVP) represents a clinical challenge. We therefore aimed to derive and validate a formula for QT estimation during RVP in a large cohort of pacemaker patients. Methods and Results We prospectively enrolled 100 patients in a derivation cohort and 487 in a validation
Amr Abdin, Alhasan Almasri, Ibrahim Antoun, Charles Gieres, Christian Werner, Yvonne Bewarder, Christian Ukena, Igor Schwantke, Michael Böhm, Saarraaken Kulenthiran   +9 more
wiley   +1 more source

Werner Irnich: Pioneer in the Development of the Dual‐Chamber Pacemaker—An Obituary

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Fifty years ago, Werner Irnich presented the concept of an optimal pacemaker capable of responding appropriately to various cardiac arrhythmias and perceptual disturbances, and intended to be used in 85% of patients. With this concept, Irnich was far ahead of his time. His proposed circuitry for AV block and atrial fibrillation, as well as his
Bernd Lemke
wiley   +1 more source

Sick Sinus Syndrome and Cerebral Venous Thrombosis: A Connection or Coincidence? A Case Report and Literature Review

Oman Medical Journal
It has been hypothesized that increased intracranial pressure (ICP) may cause sick sinus syndrome (SSS) due to its effect on vagal discharge to the heart, resulting in disruption to the sinus cycle, despite age-related degeneration of the sinoatrial node
Alawi A. Al-Attas, Njood A. Alhrkan, Muteb A. Alwatid, Saifullah M. Zaman, Mohammed F. Salawaty, Nouf A. Mansour   +5 more
doaj   +1 more source