Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang +3 more
wiley +1 more source
SINUS NODE DYSFUNCTION SYNDROME: MAKING DECISION BY QUANTUM GENETIC ALGORITHM, GRAPH NEURAL NETWORKS
Сергій Костянтинович Кулішов
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Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah +8 more
wiley +1 more source
Guillain-Barré Syndrome Presenting with Sinus Node Dysfunction and Refractory Shock
Le Dung Ha, Farrukh Abbas, Mohan Rao
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Predictive capacity of combined P-wave-indices-CHA2DS2-VASc Score in sinus node dysfunction patients without atrial fibrillation [PDF]
Haoyu Dong +9 more
openalex +1 more source
Recent animal studies have shown that the sympathetic nervous system (SNS) prevents disease activity of EAE (Experimental autoimmune encephalomyelitis, animal model of Multiple Sclerosis [MS]), presumably through adrenergic activity in the deep cervical lymph nodes (DCLNs).
Christopher Kremer +4 more
wiley +1 more source
Myocardial sleeves of the pulmonary veins in racehorses with paroxysmal atrial fibrillation exhibit upregulated pathways associated with tissue structure remodeling. Pathways related to the extracellular matrix and cellular components differ significantly from those in healthy horses.
Magdalena Arevalo‐Turrubiarte +8 more
wiley +1 more source
Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate [PDF]
Masaki Adachi +8 more
openalex +1 more source
Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review
ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira +7 more
wiley +1 more source
Early Versus Late Catheter Ablation of Atrial Fibrillation and Risk of Permanent Pacemaker Implantation in Patients With Underlying Sinus Node Dysfunction [PDF]
Muhammad Butt +5 more
openalex +1 more source

