Results 191 to 200 of about 308,108 (294)

Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training

open access: yesExperimental Physiology, EarlyView.
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto   +3 more
wiley   +1 more source

Utilising Artificial Intelligence to Identify Ventricular Tachycardia Ablation Targets in Sinus Rhythm

open access: yes
Wang X   +10 more
europepmc   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak   +3 more
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou   +11 more
wiley   +1 more source

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote ...
Udit Thakur, Jonathan M. Kalman
wiley   +1 more source

Sinus rhythm maintenance in persistent atrial fibrillation: 12-lead ECG multiscale entropy characterization. [PDF]

open access: yesMed Biol Eng Comput
Cirugeda EM   +5 more
europepmc   +1 more source

FGF23 promotes atrial fibrillation susceptibility through ETV1‐dependent sodium channel regulation and calcium handling abnormalities

open access: yesExperimental Physiology, EarlyView.
Abstract Fibroblast growth factor 23 (FGF23) is closely associated with atrial fibrillation (AF), yet whether it modulates sodium and calcium currents in atrial myocytes remains unclear. ETV1, a key transcription factor regulating atrial electrical conduction, might also be involved in FGF23‐mediated AF.
Qiaoting Yu   +7 more
wiley   +1 more source

Traumatic arteriovenous fistula after ice axe injury 27 years ago: A case report

open access: yesExperimental Physiology, EarlyView.
Abstract We report a case of a traumatic arteriovenous fistula (AVF) between the superficial femoral artery and femoral vein that went undetected for 27 years following an ice axe injury during a climbing accident in 1997. An AVF is an abnormal connection between an artery and a vein, where blood flows directly from the high‐flow arterial system to the
Kate N. Thomas   +4 more
wiley   +1 more source

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