Results 211 to 220 of about 308,108 (294)

Obstructive path to sinus rhythm: When COPD undermines AF ablation success. [PDF]

Indian Pacing Electrophysiol J
Gunawardene MA, Middeldorp ME, Sanders P.   +2 more
europepmc   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

Temporary Restoration of Sinus Rhythm Improves Outcomes of Catheter Ablation for Longstanding Persistent Atrial Fibrillation. [PDF]

J Cardiovasc Electrophysiol
Raad M, Oranefo J, Yogasundaram H, Gurin MI, Zado E, Walsh M, Markman T, Guandalini G, Hyman MC, Schaller R, Kumareswaran R, Supple G, Deo R, Nazarian S, Riley M, Lin D, Garcia F, Frankel DS, Callans D, Epstein AE, Marchlinski FE, Dixit S.   +21 more
europepmc   +1 more source

Computational model of haemodynamics during atrial fibrillation

The Journal of Physiology, EarlyView.
Abstract figure legend We developed a simplified computational model that replicates patient‐specific haemodynamics during both normal sinus rhythm and atrial fibrillation (AF). Our computational model comprises: (1) an electrical subsystem that generates unco‐ordinated atrial and irregular ventricular activation times characteristic of AF and (2) a ...
Felix Plappert, Pim J.A. Oomen, Clara E. Jones, Emmanouil Charitakis, Lars O. Karlsson, Pyotr G. Platonov, Mikael Wallman, Frida Sandberg   +7 more
wiley   +1 more source

MR-proANP, sST2, BNP and sinus rhythm maintenance 1 year after electrical cardioversion for atrial fibrillation. [PDF]

BMC Cardiovasc Disord
Badoz M, Serzian G, Favoulet B, Sellal JM, De Chillou C, Laurent G, Ecarnot F, Bardonnet K, Seronde MF, Schiele F, Meneveau N.   +10 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Prognostic Impact of Spontaneous Conversion to Sinus Rhythm in Patients With Symptomatic Paroxysmal Atrial Fibrillation: A Propensity-Matched Follow-Up Study. [PDF]

J Cardiovasc Electrophysiol
Mariani MV, Recchioni T, Pierucci N, Trivigno S, Cipollone P, Bruti RM, Laviola D, Palombi M, Matteucci A, Piro A, Chimenti C, Galardo G, Pugliese F, Vizza CD, Lavalle C.   +14 more
europepmc   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat, Jaffar Al‐Sheikhli, Andrew M. Blanks, Joseph Mayer, Nicolas Lellouche, Tarvinder Dhanjal, Christopher O'Shea   +6 more
wiley   +1 more source

The Left Atrial Appendage in Sinus Rhythm and Atrial Fibrillation: From Functional Structure to Potential Thromboembolic Reservoir, Rationale for Medical or Radical Exclusion. [PDF]

J Clin Med
Zeitani J, Likaj E, Nazzaro MS, Dibra A, Sievert K, Sievert H.   +5 more
europepmc   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source