Results 101 to 110 of about 48,649 (263)

An Optimized Multi‐Stage Drainage Cannula Design for Venoarterial Extracorporeal Membrane Oxygenation

Artificial Organs, EarlyView.
This study utilized an extensive optimization involving n = 540 design of experiments to produce a superior drainage cannula design. Compared to the clinically used Maquet model, our optimized design demonstrated reduced blood stagnation volumes, increased cannula tip velocities, and higher upper body drainage, potentially minimizing risk of thrombosis
Avishka Wickramarachchi, Mehrdad Khamooshi, Aidan Burrell, Shaun D. Gregory   +3 more
wiley   +1 more source

Multifactorial Nature of Childhood Stroke Presents a Major Challenge for Diagnosis and Management: A Population‐Based Study From Southern Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim Childhood ischemic stroke is rare but causes substantial long‐term morbidity, and its heterogeneous aetiology complicates timely diagnosis and management. Methods We conducted a retrospective population‐based observational study using hospital data and chart review to describe diagnostics, treatment and outcomes of ischemic stroke in ...
Jussi V. Leinonen, Samu Kurki, Siina Pamilo, Juho Immonen, Juha Knuuttila, Matti Hero, Mia Westerholm‐Ormio, Pirjo Isohanni, Miika Koskinen   +8 more
wiley   +1 more source

Melioidosis in companion animals: Analysis of 45 Australian cases (24 dogs; 21 cats) from 1997 to 2025 and a brief review of the animal and human literature

Australian Veterinary Journal, EarlyView.
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee, C Shilton, S Benedict, M Krockenberger, M Mayo, BJ Currie, R Malik   +6 more
wiley   +1 more source

Cerebral Venous and Sinus Thrombosis

Neurologia medico-chirurgica, 1968
The general pathology and clinical picture of cerebral venous thrombosis have been well recognized entities since the 19th century. But from our own experience of 92 cases, and from the study of cases reported in the literature, it is obvious that the diagnosis of cerebral venous thrombosis could be made with reasonable certainty only in a very few ...
openaire   +4 more sources

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

THROMBOSIS OF SUPERIOR SAGITTAL SINUS (IN SPANISH)

Revista Ciencias Biomédicas, 2014
Introduction: thrombosis of superior sagittal sinus is responsible for 0.5% of stroke cases in the world. Stroke has a mortality rate of 10% and it is more frequent in women between the fourth and fifth decade.
Remolina-López Anderson Julián, Ulloque-Caamaño Liezel, Sabogal-Barrios Rubén   +2 more
doaj  

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source

Perinatal complications, mode of delivery, and neurological morbidity in children with COL4A1/A2 variants

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To characterize reported perinatal complications and childhood neurological diagnoses among children with COL4A1/2 variants and explore associations between mode of delivery and selected neurological outcomes. Method This was a retrospective cross‐sectional patient registry study using surveys collected through the Gould Syndrome ...
Shraddha Pandey, Dawn Gano, Danielle Boyce, Rachel Vassar   +3 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Overweight and obesity are major public health challenges and well‐established risk factors for cardiovascular disease, cancer and premature mortality. We estimated the economic burden of overweight and obesity in Sweden in 2023 and projected the future economic burden in 2040 under alternative scenarios of increasing prevalence ...
Adam Fridhammar, Jovanna Dahlgren, Marije Galavazi, Lena Hjelm, Jonatan Dereke, Katarina Steen Carlsson   +5 more
wiley   +1 more source