Results 91 to 100 of about 570,641 (287)
Advanced Science, EarlyView.Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang +13 more
wiley +1 more source
A Floquet-Style Stability Analysis of the Disease-Free State in a Seasonal Hantavirus Model
MathematicsIn this study, we developed an SIR-like mathematical model of disease transmission dynamics. Hantavirus is a neglected tropical disease, and this paper presents a mathematical model of hantavirus transmission among rodents and its effect on the number of
Asep K. Supriatna +4 more
doaj +1 more source
Modeling Super-spreading Events for Infectious Diseases: Case Study SARS
, 2010 Super-spreading events for infectious diseases occur when some infected individuals infect more than the average number of secondary cases. Several super-spreading individuals have been identified for the 2003 outbreak of severe acute respiratory ...
Mkhatshwa, Thembinkosi, Mummert, Anna
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Advanced Science, EarlyView.Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe +5 more
wiley +2 more sources
Predicting COVID-19 Spread in Pakistan using the SIR Model
Journal of Pure and Applied Microbiology, 2020 The global pandemic of COVID-19 has raised several questions and attracted researchers from all of the disciplines of scientific research. Regardless of advances in science and technology, equipped laboratories of virology, high literacy rates, and ...
Syed Tahir Ali Shah +8 more
doaj +1 more source
HIV with contact-tracing: a case study in Approximate Bayesian Computation
, 2010 Missing data is a recurrent issue in epidemiology where the infection process may be partially observed. Approximate Bayesian Computation, an alternative to data imputation methods such as Markov Chain Monte Carlo integration, is proposed for making ...
Cauchemez +8 more
core +4 more sources
Resistance mechanisms matter in SIR models
Mathematical Biosciences and Engineering, 2007 We compare four SIR-style models describing behavioral or immunological disease resistance that may be both partial and temporary in parameter regions feasible for interpandemic influenza. For the models studied, backward bifurcations and bistability may occur in contexts where resistance is due to behavior change, but they do not occur when resistance
Timothy C. Reluga, Jan Medlock
openaire +3 more sources
Advanced Science, EarlyView.ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
An extension of Heston's SV model to Stochastic Interest Rates
, 2018 In 'A Closed-Form Solution for Options with Stochastic Volatility with Applications to Bond and Currency Options', Heston proposes a Stochastic Volatility (SV) model with constant interest rate and derives a semi-explicit valuation formula.
de Frutos, Javier, Gaton, Victor
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