Results 121 to 130 of about 68,228 (285)

Branched‐chain amino acids and all‐cause mortality in patients with liver cirrhosis, and the onset of diabetes in liver transplant recipients

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Our study demonstrates that total BCAA levels increase following liver transplantation. In patients with cirrhosis, higher total BCAA levels are associated with a reduced risk of all‐cause mortality. However, while this association is not observed in liver transplant recipients, elevated total BCAA levels are strongly linked to an increased risk of new‐
Yakun Li   +9 more
wiley   +1 more source

Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing. [PDF]

open access: yes, 2019
Despite being one of the most common cancers, treatment options for prostate cancer are limited. Novel approaches for advanced disease are needed. We evaluated the relative rate of use of clinical-grade next generation sequencing (NGS) in prostate cancer,
Carter, Jennifer L   +4 more
core  

Palmitoylethanolamide (PEA) Induces an Increase in Spleen Regulatory T Cells, Reduces CD8+ Cells and TNF‐α Levels in Target Organs, and Protects Mice From Graft‐Versus‐Host Disease‐Related Mortality Through PPAR Activation Without Compromising the Graft‐Versus‐Tumour Response

open access: yesImmunology, EarlyView.
Effect of Palmitoylethanolamide (PEA) in a murine model of graft‐versus‐host disease (GVHD). Following an allogeneic transplant from C57BL/6J donors to BALB/c recipients, PEA treatment improved survival, alleviated clinical symptoms, and protected target organs in GVHD‐affected mice.
Bárbara Betônico Berg   +9 more
wiley   +1 more source

Long-term efficacy and safety of sirolimus therapy in patients with lymphangioleiomyomatosis

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Sirolimus has been confirmed to be effective for lymphangioleiomyomatosis (LAM), a rare multisystem neoplastic disease in women. The long-term effects of sirolimus treatment for LAM, however, are largely unknown.
Siqi Hu   +8 more
doaj   +1 more source

Exploring the Influence of Oral and Gut Microbiota on Ulcerative Mucositis: A Pilot Cohort Study

open access: yesOral Diseases, Volume 31, Issue 6, Page 1776-1788, June 2025.
ABSTRACT Aim Comparing oral and gut microbiome profiles between patients with and without ulcerative mucositis during allogeneic stem cell transplantation (aSCT). Materials and Methods Specimens from oral mucosa, saliva, and stool were collected pre‐(T0) and post‐ (T0 +28d ± 14d) aSCT (T1).
Valentin Bartha   +9 more
wiley   +1 more source

Sirolimus

open access: yesAmerican Journal of Health-System Pharmacy, 2022
openaire   +2 more sources

Adding to Your Tool Box: Laser Therapy for Vascular Anomalies

open access: yesPediatric Dermatology, Volume 42, Issue 4, Page 716-727, July/August 2025.
ABSTRACT Adjuvant laser therapy of vascular anomalies is based on the principle of selective photo‐thermolysis, through targeted destruction of selected chromophores with minimal injury to surrounding tissue. Choice of laser wavelength, treatment parameters, and predicted response to therapy are dependent on the dominant chromophore within the vascular
Kevin V. Thomas   +8 more
wiley   +1 more source

The role of acquired host immunity in periodontal diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane   +2 more
wiley   +1 more source

Aspergillus After Lung Transplantation: Prophylaxis, Risk Factors, and the Impact on Chronic Lung Allograft Dysfunction

open access: yesTransplant Infectious Disease, EarlyView.
Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert   +7 more
wiley   +1 more source

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