Results 121 to 130 of about 60,209 (283)
International Journal of Nanomedicine, 2012 Ha Na Woo1*, Hye Kyung Chung2*, Eun Jin Ju1, Joohee Jung1,3, Hye-Won Kang4, Sa-Won Lee4, Min-Hyo Seo4, Jin Seong Lee5, Jung Shin Lee1,6, Heon Joo Park7, Si Yeol Song1,8, Seong-Yun Jeong1, Eun Kyung Choi1,2,81Institute for Innovative Cancer Research ...
Woo HN +12 more
doaj
Transplant Infectious Disease, EarlyView.Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert +7 more
wiley +1 more source
Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components
Modern Agriculture, Volume 3, Issue 1, June 2025.The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li +3 more
wiley +1 more source
Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing. [PDF]
, 2019 Despite being one of the most common cancers, treatment options for prostate cancer are limited. Novel approaches for advanced disease are needed. We evaluated the relative rate of use of clinical-grade next generation sequencing (NGS) in prostate cancer,
Carter, Jennifer L +4 more
core
Oral mucosal injury caused by mammalian target of rapamycin inhibitors: emerging perspectives on pathobiology and impact on clinical practice. [PDF]
, 2016 In recent years oral mucosal injury has been increasingly recognized as an important toxicity associated with mammalian target of rapamycin (mTOR) inhibitors, including in patients with breast cancer who are receiving everolimus.
Campbell-Baird, Cynthia +12 more
core
American Journal of Hematology, Volume 100, Issue 5, Page 830-839, May 2025.ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina +19 more
wiley +1 more source
Efavirenz and Dolutegravir May Alter Sirolimus Metabolism in People Living with HIV [PDF]
Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor commonly used to prevent organ rejection in transplant recipients was evaluated for safety and efficacy to reduce latent HIV reservoirs in people with HIV (PWH) on chronic suppressive ...
Kuo-Esser, Laurence
core +1 more source
RAS Pathway Mutations and Therapeutics in Vascular Anomalies
Pediatric Blood &Cancer, Volume 72, Issue 5, May 2025.ABSTRACT Vascular anomalies (VAs) are a diverse group of vascular tumors and vascular malformations (VMs). VMs are characterized by abnormal vessel development, overgrowth, and dysfunction. Coagulopathy, edema, and effusions can cause severe morbidity and mortality in children and adults with these diseases. Germline or somatic mutations in the RAS/RAF/
Sara Alharbi +4 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 5, May 2025.ABSTRACT Aim Calcineurin inhibitors (CNIs) have revolutionized transplant medicine, improving allograft survival but posing challenges like calcineurin inhibitor‐induced nephrotoxicity (CNT). Acute CNT, often dose‐dependent, leads to vasoconstriction and acute kidney injury, with treatment focusing on CNI exposure reduction.
Carla M. Hansen +4 more
wiley +1 more source