Results 1 to 10 of about 6,813 (202)

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Lymphangioleiomyomatosis of the lungs: features of the clinical picture, diagnosis and treatment. Case report

Consilium Medicum, 2022
The article highlights the main issues of etiology, pathogenesis, clinical picture, diagnosis and treatment of patients with lymphangioleiomyomatosis. The clinical observation presents the features of the condition, the rate of progression, diagnostic ...
Galina L. Ignatova, Elena V. Blinova, Mariia S. Bel'sner   +2 more
doaj   +1 more source

Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease

Respirology, Volume 31, Issue 6, Page 599-609, June 2026.
ABSTRACT Background and Objective Interstitial lung diseases (ILDs) lead to breathlessness, cough, deteriorating quality of life and early death. Patients are typically diagnosed late in their disease course when existing lung damage cannot be reversed.
Caitlin C. Fermoyle, John Townend, Vidya Navaratnam, Nicole Goh, Francesca Gonnelli, Neva Eleangovan, Ursie Smith, Heath Heatley, Victoria Carter, David B. Price, Richard Hubbard, Tamera J. Corte   +11 more
wiley   +1 more source

Low-dose sirolimus in retroperitoneal lymphangioleiomyomas

Lung India, 2019
Lymphangioleiomyomatosis (LAM) is a rare disease associated with cystic lung destruction and abdominal tumors, including lymphangioleiomyomas, which frequently occur in the retroperitoneal region.
Kamonpun Ussavarungsi, Archana T Laroia, Charles D Burger   +2 more
doaj   +1 more source

Risk Factors for Waiting List Mortality in Lung Transplant Candidates With Post‐Hematopoietic Stem Cell Transplantation Non‐Infectious Pulmonary Complications

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Background Late‐onset non‐infectious pulmonary complications (LONIPCs) following hematopoietic stem cell transplantation (HSCT) are a known indication for need of lung transplantation. This study aimed to clarify the clinical characteristics of patients with LONIPCs after HSCT who were registered for lung transplantation and reveal the risk ...
Hisao Higo, Satoru Senoo, Satoko Makimoto, Tomohiro Nagano, Takumi Kondo, Haruchika Yamamoto, Shin Tanaka, Kentaroh Miyoshi, Seiichiro Sugimoto, Shinichi Toyooka, Yoshinobu Maeda, Yosuke Togashi, Nobuaki Miyahara   +12 more
wiley   +1 more source

A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult

Journal of the ASEAN Federation of Endocrine Societies
A 23-year-old female smoker presented in late 2008 with a large left pneumothorax. She had multiple spontaneous pneumothoraces in 2007 which required pleurectomy.
Chng Chiaw Ling
doaj   +1 more source

Chronic pelvic pain due to pelvic lymphangioleiomyomatosis: A case report

Gynecology and Minimally Invasive Therapy, 2016
Lymphangioleiomyomatosis (LAM), a rare multisystem disease affecting mainly young women, is characterized by an abnormal proliferation of smooth muscle-like cells in the lungs. We report a case of endometriosis with chronic pelvic pain due to pelvic LAM.
Tetsu Wakimoto, Tateki Tsutsui, Mahiru Kawano, Namhyo Kim, Akihiro Moriyama, Tadashi Kimura   +5 more
doaj   +1 more source

Comparison of Signal‐ and Volume‐Based Ventilation‐Weighted Assessment Using 3D FLORET UTE MRI in Patients With Various Pulmonary Disease

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2814-2827, May 2026.
ABSTRACT Purpose 3D free‐breathing, proton, contrast‐agent‐free MR methods are increasingly used for pulmonary ventilation‐weighted measurements. The methods are split between: (1) signal‐based, which rely on lung parenchyma signal changes during respiration, and (2) volume‐based that utilize the Jacobian determinant of deformation fields from the ...
Filip Klimeš, Joseph W. Plummer, Andreas Voskrebenzev, Marcel Gutberlet, Marius M. Klein, Matthew M. Willmering, Alexander M. Matheson, Abdullah S. Bdaiwi, Frank Wacker, Jason C. Woods, Zackary I. Cleveland, Laura L. Walkup, Jens Vogel‐Claussen   +12 more
wiley   +1 more source

Glutaredoxin‐1 promotes lymphangioleiomyomatosis progression through inhibiting Bim‐mediated apoptosis via COX2/PGE2/ERK pathway

Clinical and Translational Medicine, 2023
Background Lymphangioleiomyomatosis (LAM) is a female‐predominant interstitial lung disease, characterized by progressive cyst formation and respiratory failure.
Ya Feng, Tianjiao Li, Yin Li, Zhoujun Lin, Xiao Han, Xiaolin Pei, Yupeng Zhang, Fei Li, Juan Yang, Di Shao, Chenggang Li   +10 more
doaj   +1 more source

Japanese Clinical Practice Guidelines for Vascular Tumors, Vascular Malformations, Lymphatic Malformations, and Lymphangiomatosis 2022

The Journal of Dermatology, Volume 53, Issue 5, Page e257-e356, May 2026.
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita, Kosuke Ishikawa, Sadanori Akita, Katsuyoshi Koh, Satoru Sasaki, Masatoshi Jinnin, Hidefumi Mimura, Keigo Osuga, Michio Ozeki, Michiko Nagahama, Akihiro Fujino, Yoko Aoki, Akiko Asai, Noriko Aramaki‐Hattori, Ryohei Ishiura, Masanori Inoue, Yuki Iwashina, Takafumi Ohshiro, Keiko Ogawa, Mine Ozaki, Junko Ochi, Shiro Onozawa, Motoi Kato, Takahide Kaneko, Tamihiro Kawakami, Akira Kitagawa, Masakazu Kurita, Yoshihiro Kuwano, Taro Kono, Shien Seike, Shinsuke Takagi, Nobuyuki Takakura, Takao Tachibana, Shuichi Tanoue, Kumiko Chuman, Hiroki Nakaoka, Yasuhiro Nakamura, Fumio Nagai, Yasunari Niimi, Shunsuke Nosaka, Taiki Nozaki, Tadashi Nomura, Kazuki Hashimoto, Ayato Hayashi, Satoshi Hirakawa, Takeshi Hirabayashi, Taizo Furukawa, Hiroshi Furukawa, Yumiko Hori, Takanobu Maekawa, Kentaro Matsuoka, Hideki Mori, Eiichi Morii, Akira Morimoto, Yuta Moriwaki, Shunsuke Yuzuriha, Naoaki Rikihisa, Munezumi Fujita, Yasuyuki Yamahana, Kyoichi Deie, Asami Tozawa, Daisuke Hasegawa, Akira Higashiyama, Daisuke Maeda, Sachiko Asayama, Yuhki Arai, Yohei Iwata, Mayu Uka, Hidehito Usui, Mizuki Uchiyama, Saori Endo, Hideki Endo, Rintaro Ono, Naoya Oshima, Toshihiro Otsuka, Kuniaki Ohara, Shinji Kagami, Tomo Kakihara, Mototoshi Kato, Hiroki Kanamori, Masafumi Kamata, Ami Kawaguchi, Akiko Kishi, Hiroshi Kitagawa, Kiyokazu Kim, Tamotsu Kobayashi, Takeshi Saito, Yusuke Shikano, Shuichi Shimada, Keisuke Suzuki, Masataka Takahashi, Shohei Takami, Reiko Takeda, Aya Tanaka, Kaishu Tanaka, Satoru Tamura, Masashi Tamura, Kanako Danno, Kenji Tsuboi, Yuta Nakajima, Ryo Nakatani, Miho Noguchi, Akifumi Nozawa, Naoki Hashizume, Masashi Hayakawa, Daichi Hayashi, Takaya Fukumoto, Mamoru Honda, Norifumi Matsuda, Hayato Maruguchi, Naoki Murakami, Kiichiro Yaguchi, Shiho Yasue, Hiroki Yoshihara, Rika Yoshimatsu, Kiyohito Yamamoto, Shinji Wada   +116 more
wiley   +1 more source