Results 151 to 160 of about 117,912 (291)

The patient perspective on sirolimus for epithelioid hemangioendothelioma (EHE): results of a community survey highlighting the importance of equitable access to treatments

Frontiers in Oncology
BackgroundEpithelioid hemangioendothelioma (EHE) is an ultra-rare, vascular sarcoma with clinical presentation ranging from an indolent to an aggressive form.
Denise Robinson, Hugh Leonard, Giacomo Giulio Baldi, William D. Tap, Robin L. Jones, Silvia Stacchiotti, Pan Pantziarka, Pan Pantziarka   +7 more
doaj   +1 more source

Supplementary Figure 3 from Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma

, 2023
Filip Jankú, Haeseong Park, S. Greg Call, Kiran Madwani, Yasuhiro Oki, Vivek Subbiah, David S. Hong, Aung Naing, Vivianne M. Velez-Bravo, Tamara G. Barnes, Fredrick B. Hagemeister, Gerald S. Falchook, Daniel D. Karp, Jennifer J. Wheler, Sarina A. Piha‐Paul, Ignacio Garrido‐Laguna, Elizabeth J. Shpall, Luis Fayad, Sattva S. Neelapu, Funda Meric‐Bernstam, Razelle Kurzrock, Michelle A. Fanale   +21 more
openalex   +1 more source

Coronary Computed Tomography Angiography for the Assessment of Sirolimus-Eluting Resorbable Magnesium Scaffold [PDF]

, 2022
Elisabetta Tonet, Alberto Cossu, Graziella Pompei, Rossella Ruggiero, Serena Caglioni, Daniela Mele, Alberto Boccadoro, Marco Micillo, Marta Helena Cocco, Martina De Raffele, Melchiore Giganti, Simone Biscaglia, Fabio Sgura, Gerlando Preti, Youbing Yin, Yi Wang, Giorgio Quadri, Enrico Cerrato, Gianluca Campo   +18 more
openalex   +1 more source

Sirolimus therapy for fetal cardiac rhabdomyoma in a pregnant woman with tuberous sclerosis

Obstetrics & Gynecology Science, 2019
Rhabdomyoma is the most common fetal cardiac tumor, and its development is related to tuberous sclerosis. Fetal cardiac rhabdomyomas often spontaneously regress in utero or after birth, but large tumors can cause hemodynamic obstruction.
Hyea Park, Chi-Son Chang, Suk-Joo Choi, S. Oh, C. Roh   +4 more
semanticscholar   +1 more source

Adalimumab‐responsive Monogenic Inflammatory Bowel Disease With Pseudopolyposis Characteristic of TGFBR2 Variant in Loeys‐Dietz Syndrome

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Loeys‐Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder caused by pathogenic variants in TGFBR1 or TGFBR2. It is characterized by vascular fragility, skeletal abnormalities, and predisposition to allergic and inflammatory conditions, including monogenic inflammatory bowel disease (IBD).
Tomomitsu Sado, Satoshi Ukai, Shingo Kurasawa, Yosuke Kono, Norio Hasuda, Mai Iwaya, Takaya Nakane, Tomomi Yamaguchi, Tomoki Kosho, Yoshiko Nakayama   +9 more
wiley   +1 more source

Long-term efficacy and safety of sirolimus therapy in patients with lymphangioleiomyomatosis

Orphanet Journal of Rare Diseases, 2019
Background Sirolimus has been confirmed to be effective for lymphangioleiomyomatosis (LAM), a rare multisystem neoplastic disease in women. The long-term effects of sirolimus treatment for LAM, however, are largely unknown.
Siqi Hu, Xiuxiu Wu, Wenshuai Xu, Xinlun Tian, Yanli Yang, Shao-Ting Wang, Song Liu, Xingxiang Xu, Kai-Feng Xu   +8 more
doaj   +1 more source

Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia IIb

Brain Pathology, Volume 36, Issue 2, March 2026.
Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal, Kevin Faust, Okty Abbasi Borhani, Mugeng Liu, Lauren Omoto, Evelyn Rose Kamski‐Hennekam, Parsa Babaei Zadeh, Rifat Shahriar Sajid, Phedias Diamandis   +8 more
wiley   +1 more source

Coadministration of fluconazole to boost subtherapeutic sirolimus concentrations: A case report

Pharmacology Research & Perspectives
Individual sirolimus whole blood concentrations are highly variable, critically influenced by the concomitant use of cytochrome P450 (CYP) 3A inducers or inhibitors, and also modulated by food.
Camilo Scherkl, Andreas D. Meid, Sven E. Cuntz, Laura Classen, Johanna Weiss, David Czock, Walter E. Haefeli   +6 more
doaj   +1 more source

Long-Term Effect of Sirolimus on Serum Vascular Endothelial Growth Factor D Levels in Patients With Lymphangioleiomyomatosis [PDF]

, 2017
Angelo M. Taveira‐DaSilva, Amanda M. Jones, Patricia Julien-Williams, Mario Stylianou, Joel Moss   +4 more
openalex   +1 more source

New Insights Into Factors Shaping CMV‐Specific T‐Cell Polyfunctionality After Hematopoietic Cell Transplantation

American Journal of Hematology, Volume 101, Issue 2, Page 255-268, February 2026.
ABSTRACT Polyfunctional cytomegalovirus (CMV)‐specific T cells are critical for antiviral immunity in allogeneic hematopoietic cell transplantation (HCT) recipients. However, gaps remain in managing refractory CMV and optimizing virus‐specific cellular therapy (VST).
Alicja Sadowska‐Klasa, Fang Yun Lim, Hu Xie, Danniel Zamora, Terry Stevens‐Ayers, Wendy M. Leisenring, Bradley C. Edmison, Stephen C. De Rosa, Marco Mielcarek, Michael Boeckh   +9 more
wiley   +1 more source