Results 161 to 170 of about 117,912 (291)

Late Vascular Responses From 2 to 4 Years After Implantation of Sirolimus-Eluting Stents [PDF]

open access: bronze, 2010
Masamichi Takano   +11 more
openalex   +1 more source

Immunophenotypic abnormality quantification refines multiparameter flow cytometry‐based measurable residual disease testing in adults allografted for acute myeloid leukemia in morphologic remission

open access: yesHemaSphere, Volume 10, Issue 2, February 2026.
Abstract Flow cytometry‐based measurable residual disease (MRD) testing is routinely used in acute myeloid leukemia (AML), but methodologies need refinement to optimize assay characteristics. Here, we examined 1215 adults with AML or myelodysplastic syndrome/AML allografted in morphologic remission to study how the type(s) of leukemic blasts and degree/
Calvin M. Le   +8 more
wiley   +1 more source

Lung Transplantation Outcomes and Peritransplant Sirolimus Use in Lymphangioleiomyomatosis

open access: yesAnnals of Thoracic Surgery Short Reports
Background: With the introduction of sirolimus as medical therapy for lymphangioleiomyomatosis (LAM), an updated evaluation of LAM lung transplant (LT) outcomes and characterization of peritransplant sirolimus use is needed.
Emily L. Larson, BS   +11 more
doaj   +1 more source

Clinical presentation, treatment, and outcome of children with primary intestinal lymphangiectasia: A national retrospective study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 398-406, February 2026.
Abstract Objectives Primary intestinal lymphangiectasia (PIL) is a very rare disease responsible for protein‐losing enteropathy. There is little published data about treatments efficacy and outcomes. Our main objective was to describe the clinical profile, response to therapy, and outcomes of children with PIL.
Noémie Goret   +12 more
wiley   +1 more source

Non‐Melanoma Skin Cancer in Transplant Recipients: A Single‐Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes

open access: yesClinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Background Non‐melanoma skin cancer (NMSC) is a frequent long‐term complication in transplant recipients, mainly due to chronic immunosuppression. Its incidence varies by transplant type and regimen, but existing evidence is often fragmented.
Corrado Zengarini   +7 more
wiley   +1 more source

Pericardial and pleural effusions associated with sirolimus and discussion of possible mechanisms [PDF]

open access: yes, 2012
Sirolimus, a mammalian target of rapamycin inhibitor, is an increasingly used immunosuppressant in solid-organ transplantation. There are an increasing number of reports of unusual oedematous adverse effects associated with this drug, including ...
Almeida, M.   +6 more
core  

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

open access: yesHistopathology, Volume 88, Issue 3, Page 698-709, February 2026.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai   +6 more
wiley   +1 more source

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD) [PDF]

open access: yes, 2017
Background. Autosomal dominant polycystic kidney disease (ADPKD) is characterized by dysregulated tubular epithelial cell growth, resulting in the formation of multiple renal cysts and progressive renal failure.
Hall, Michael N.   +5 more
core  

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