Results 171 to 180 of about 68,914 (294)

Dual Roles of Autophagy in Radiation‐Induced Brain Injury: Mechanistic Insights and Therapeutic Implications

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.
Under varying conditions, autophagy plays a dualistic role in radiation‐induced brain injury (RIBI), interacting intricately with apoptosis, ferroptosis, neuroinflammation, oxidative stress, blood–brain barrier (BBB) disruption, mitophagy, endoplasmic reticulum (ER) stress, and mitochondrial biogenesis.
Jiayu Tian   +6 more
wiley   +1 more source

Sirolimus: A Potential Chemopreventive Agent [PDF]

open access: yesJournal of Investigative Dermatology, 2008
Anthony P. Fernandez   +2 more
openaire   +3 more sources

Association of Cardiovascular Biomarkers With Cardiac Allograft Vasculopathy and Atherosclerotic Coronary Artery Disease

open access: yesClinical Transplantation, Volume 39, Issue 6, June 2025.
ABSTRACT Background: Cardiac allograft vasculopathy (CAV) remains a barrier to long‐term survival after heart transplantation. Little is known about cardiovascular biomarkers in CAV and how they compare to biomarkers in atherosclerotic coronary artery disease (CAD).
Lukas Köster   +12 more
wiley   +1 more source

Transplacental sirolimus: a new treatment strategy for life-threatening fetal cardiac rhabdomyomas-a case report. [PDF]

open access: yesOrphanet J Rare Dis
Uno K   +6 more
europepmc   +1 more source

Efficacy and Safety of Combining r‐ATG With PTCy for GvHD Prophylaxis in Haploidentical HSC Transplantation for Malignancies—A Systematic Review

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Allogeneic haematopoietic stem cell transplantation (HSCT) for haematological malignancies can cause acute and chronic graft‐versus‐host disease (GvHD), impacting graft success and mortality. Rabbit anti‐thymocyte globulin (r‐ATG) or post‐transplant cyclophosphamide (PTCy) is effective in reducing GvHD in haploidentical‐HSCT.
Joseph M. John   +3 more
wiley   +1 more source

Mortality in Tuberous Sclerosis Complex in the United Kingdom, 2016–2022

open access: yesJournal of Intellectual Disability Research, Volume 69, Issue 6, Page 457-464, June 2025.
ABSTRACT Background Tuberous sclerosis complex (TSC) is a genetic condition caused by mutations in either TSC1 or TSC2 genes, affecting around two million people globally. This study aims to examine causes of death in TSC and explore factors contributing to mortality in people with TSC in the United Kingdom in recent years following updated management ...
Callum Richard Thomas Kidson   +2 more
wiley   +1 more source

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