Results 31 to 40 of about 2,624 (172)

Global studies in social determinants of health in people with Alzheimer´s disease

Alzheimer's &Dementia, Volume 21, Issue S6, December 2025.
Abstract Background Social, behavioral, and environmental determinants of health (SDOH), such as access to and quality of education and healthcare, and socioeconomic factors, influence health outcomes, including dementia. We aim to identify the main SDOH associated with Alzheimer's disease (AD) by comparing AD cases to cognitively unimpaired (CU ...
Maryenela Illanes‐Manrique, Pilar Giron‐Davila, Larry D Adams, Sheila Castro‐Suarez, Julia Rios‐Pinto, Pedro R Mena, Elison Sarapura‐Castro, Farid Rajabli, Ivan Cornejo‐Herrera, Katalina F. McInerney, Michael L Cuccaro, Jeffery M Vance, Angel Medina‐Colque, Koni Mejia‐Rojas, Edward Ochoa‐Valle, Serggio Lanata, Aldo Vences‐Balta, Eden R. Martin, Giuseppe Tosto, Margaret Pericak‐Vance, Mario Cornejo‐Olivas   +20 more
wiley   +1 more source

A novel stop‐gain SORL1 mutation from Amerindian background in a Peruvian family with Alzheimer’s Disease of the PeADI Study

Alzheimer's &Dementia, Volume 20, Issue S1, December 2024.
Abstract Background Common and rare variants in SORL1 have been associated with increased risk of Alzheimer’s disease (AD). Since 2019, we have run an international collaborative research initiative to ascertain a Peruvian cohort for Alzheimer’s disease and other related dementias for genetic studies (PeADI).
Mario Cornejo‐Olivas, Anthony J. Griswold, Ana Saldarriaga‐Mayo, Pedro R. Mena, Richard S. Rodriguez, Larry D. Adams, Patrice L. Whitehead, Rosario Isasi, Maryenela Illanes‐Manrique, Elison Sarapura‐Castro, Farid Rajabli, Katalina F McInerney, Karina Milla‐Neyra, Carla Manrique‐Enciso, Gary W Beecham Jr., Sheila Castro‐Suarez, Peter St George‐Hyslop, Ismael Araujo‐Aliaga, Michael L. Cuccaro, Jeffery M. Vance, Margaret A Pericak‐Vance   +20 more
wiley   +1 more source

Clinical profile of Amnestic Early‐Onset Alzheimer’s disease in Peru: Case Series from a Neurological Care Center

Alzheimer's &Dementia, Volume 20, Issue S3, December 2024.
Abstract Background Early‐onset Alzheimer’s disease (EOAD) is a rare and devasting form of Alzheimer disease that represents 5‐10% of the total number of Alzheimer disease (AD). It is significantly less well studied than the late‐onset form of AD. The clinical presentation is heterogeneous, the amnestic variant is the most frequent (75%).
Sheila Castro‐Suarez, Erik Alberto Guevara‐Silva, Kelvin Alvarez‐Toledo, Cesar Caparo‐Zamalloa, Jonathan Adrian Zegarra‐Valdivia, Maria Meza‐Vega   +5 more
wiley   +1 more source

Attitudes and Perceptions of Caregivers of person with Frontotemporal Dementia in Peru: Preliminary results

Alzheimer's &Dementia, Volume 20, Issue S4, December 2024.
Abstract Background Frontotemporal dementia (FTD) is a clinical syndrome characterized by progressive changes in behavior, executive function, or language. In Latin America, persons with FTD are underrecognized or diagnosed late. There is a lack of knowledge about the experiences have on families.
Sheila Castro‐Suarez, Maryenela Z. Illanes‐Manrique, Maria Meza‐Vega, José Cuenca, Serggio Lanata, Mario Cornejo‐Olivas   +5 more
wiley   +1 more source

Importancia del sistema nervioso central

Revista Semilla Científica
El propósito de este artículo es revisar el estado actual del conocimiento sobre la importancia del Sistema Nervioso Central (SNC). Se aplicó una metodología de revisión bibliográfica exhaustiva, analizando artículos científicos y libros especializados publicados en los últimos 10 años. Los hallazgos más relevantes indican que el SNC desempeña un papel
Lourdes Cáceres, Luis Ruiz, Angelique Robles, Sindy Ortiz   +3 more
openaire   +1 more source

Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research

Alzheimer's &Dementia, Volume 20, Issue 12, Page 9014-9036, December 2024.
Abstract Frontotemporal dementia (FTD) is one of the leading causes of young‐onset dementia before age 65, typically manifesting as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). Although FTD affects all populations across the globe, knowledge regarding the pathophysiology and genetics derives ...
Karen Nuytemans, Sanne Franzen, Iris J. Broce, Paulo Caramelli, Ratnavalli Ellajosyula, Elizabeth Finger, Veer Gupta, Vivek Gupta, Ignacio Illán‐Gala, Samantha M. Loi, Darby Morhardt, Yolande Pijnenburg, Katya Rascovsky, Monique M. Williams, Jennifer S. Yokoyama, Juliana Acosta‐Uribe, Rufus Akinyemi, Suvarna Alladi, Biniyam A. Ayele, Yavuz Ayhan, Renelle Bourdage, Sheila Castro‐Suarez, Leonardo Cruz de Souza, Penny Dacks, Sterre C. M. de Boer, Jessica de Leon, Shana Dodge, Stephanie Grasso, Nupur Ghoshal, Vidyulata Kamath, Fiona Kumfor, Jordi A. Matias‐Guiu, Pauline Narme, T. Rune Nielsen, Daniel Okhuevbie, Stefanie Piña‐Escudero, Ramiro Ruiz‐Garcia, Brigid Ryan, Marta Scarioni, Andrea Slachevsky, Aida Suarez‐Gonzalez, Boon Lead Tee, Elena Tsoy, Hulya Ulugut, Chiadi U. Onyike, Ganesh M. Babulal, ISTAART Frontotemporal Dementia and Related Disorders PIA, ISTAART Diversity and Disparities PIA   +47 more
wiley   +1 more source

Whole‐body non‐forensic fetal virtopsy using postmortem magnetic resonance imaging at 7 Tesla vs classical autopsy

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 661-668, November 2024.
ABSTRACT Objective To determine the diagnostic accuracy of virtual autopsy using whole‐body postmortem ultra‐high field magnetic resonance imaging (MRI) at 7 Tesla (T), using a short T2‐weighted imaging (T2‐WI) protocol, compared with classical autopsy, for detecting structural abnormalities in small second‐trimester fetuses. Methods Thirty consecutive
A. Staicu, C. Albu, R. Popa‐Stanila, C. Bondor, L. Chiriac, D. Eniu, I. Goidescu, A. R. Florian, M. Surcel, G. Cruciat, D. Muresan, I. Rotar   +11 more
wiley   +1 more source

El marco de razonamiento clínico de Bobath: Un modelo de ciencia de sistemas para abordar la complejidad de los trastornos del neurodesarrollo incluida la parálisis cerebral

Developmental Medicine &Child Neurology, Volume 66, Issue 8, Page e120-e129, August 2024.
Resumen La actual práctica de desarrollo Bobath recomendada dentro del Marco de Razonamiento Clínico Bobath (BCRF) puede conceptualizarse utilizando la visión de la ciencia de los sistemas. Proporciona, así, una perspectiva holística de la interrelación e interconexión de las variables asociadas con la discapacidad aparecida durante la infancia.
Margaret J. Mayston, Gillian M. Saloojee, Sarah E. Foley   +2 more
wiley   +1 more source

Diagnostic yield of exome sequencing in prenatal agenesis of corpus callosum: systematic review and meta‐analysis

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 3, Page 312-320, March 2024.
ABSTRACT Objectives To determine the incremental diagnostic yield of exome sequencing (ES) after negative chromosomal microarray analysis (CMA) in cases of prenatally diagnosed agenesis of the corpus callosum (ACC) and to identify the associated genes and variants.
H. J. Mustafa, J. P. Barbera, E. V. Sambatur, G. Pagani, Y. Yaron, C. D. Baptiste, R. J. Wapner, C. J. Brewer, A. Khalil   +8 more
wiley   +1 more source

Actualidad en la patología y tratamiento de los gangliogliomas: ¡un tumor no tan benigno!

Acta Neurológica Colombiana, 2023
Los gangliogliomas (GG) se definen como tumores mixtos conformados por células de glía y neurona; son considerados como benignos, sin embargo hay reportes de GG que se diferencian por ser tumores de alto grado tipo glioblastoma; este cambio se observa ...
Fernando González Trujillo, Pedro Penagos González, Camilo Zubieta, Gonzalo Melo Gómez, Alfredo Ernesto Romero Rojas, Gonzalo Guevara, Fabián Neira, Jimy Medina   +7 more
doaj   +2 more sources