Results 1 to 10 of about 379,448 (262)

Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

open access: yesFrontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu   +12 more
doaj   +1 more source

Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response

open access: yesCommunications Biology, 2022
Using Epstein-Barr virus (EBV) infection of human B cells, the importance of peroxisomal very long-chain fatty acid transport involving ABCD1 in viral infection and host defence is elucidated and applicable also to other herpes- and coronaviruses.
Isabelle Weinhofer   +16 more
doaj   +1 more source

Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis

open access: yesSignal Transduction and Targeted Therapy, 2023
Amyotrophic lateral sclerosis (ALS) is a devastating fatal neurodegenerative disease with no cure. Receptor-interacting protein kinase 1 (RIPK1) has been proposed to mediate pathogenesis of ALS.
Jun Wei   +11 more
doaj   +1 more source

Enteric synucleinopathy: real entity or only a trendy concept?

open access: yesFree Neuropathology, 2020
An accumulating body of literature has emerged in the past 25 years to show that Parkinson’s disease (PD) is not only a disorder of the brain but also of the gastrointestinal tract and more generally of the gut-brain axis. Gastrointestinal symptoms occur
Adrien de Guilhem de Lataillade   +4 more
doaj   +1 more source

NOD1/RIP2 signalling enhances the microglia-driven inflammatory response and undergoes crosstalk with inflammatory cytokines to exacerbate brain damage following intracerebral haemorrhage in mice

open access: yesJournal of Neuroinflammation, 2020
Background Secondary brain damage caused by the innate immune response and subsequent proinflammatory factor production is a major factor contributing to the high mortality of intracerebral haemorrhage (ICH).
Miao Wang   +15 more
doaj   +1 more source

The 17th National Annual Conference on Neurological Infectious Diseases and Cerebrospinal Fluid Cytology of the Chinese Medical Association Neurology Branch was successfully held

open access: yesBrain Hemorrhages, 2021
The 17th National Annual Conference on Neurological Infectious Diseases and Cerebrospinal Fluid Cytology of the Chinese Medical Association Neurology Branch was successfully held in Wuhan, Hubei, China.
Ge Zhang   +5 more
doaj   +1 more source

Standards in neurosonology. Part III [PDF]

open access: yesJournal of Ultrasonography, 2016
The paper presents standards related to ultrasound imaging of the cerebral vasculature and structures. The aim of this paper is to standardize both the performance and description of ultrasound imaging of the extracranial and intracranial cerebral ...
Joanna Wojczal   +5 more
doaj   +1 more source

Dyslipidemic Diet Induces Mobilization of Peripheral Neutrophils and Monocytes That Exacerbate Hemorrhagic Brain Injury and Neuroinflammation

open access: yesFrontiers in Cellular Neuroscience, 2020
Background: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition characterized by a significant accumulation of lipids in the liver without excessive alcohol consumption.
Xiuping Li   +12 more
doaj   +1 more source

MicroRNA-Mediated Silencing Pathways in the Nervous System and Neurological Diseases

open access: yesCells, 2022
MicroRNAs (miRNAs) are small noncoding RNAs that play a prominent role in post-transcriptional gene regulation mechanisms in the brain tuning synaptic plasticity, memory formation, and cognitive functions in physiological and pathological conditions [...]
openaire   +4 more sources

Standards in neurosonology. Part I

open access: yesJournal of Ultrasonography, 2015
The paper presents standards related to ultrasound imaging of the cerebral vasculature and structures. The aim of this paper is to standardize both the performance and description of ultrasound imaging of the extracranial and intracranial cerebral ...
Joanna Wojcza   +5 more
doaj   +1 more source

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