Results 11 to 20 of about 540,580 (353)

Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy

open access: yesFrontiers in Neurology, 2021
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
S. Bhagavati
semanticscholar   +1 more source

Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

open access: yesFrontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu   +12 more
doaj   +1 more source

Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response

open access: yesCommunications Biology, 2022
Using Epstein-Barr virus (EBV) infection of human B cells, the importance of peroxisomal very long-chain fatty acid transport involving ABCD1 in viral infection and host defence is elucidated and applicable also to other herpes- and coronaviruses.
Isabelle Weinhofer   +16 more
doaj   +1 more source

Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis

open access: yesSignal Transduction and Targeted Therapy, 2023
Amyotrophic lateral sclerosis (ALS) is a devastating fatal neurodegenerative disease with no cure. Receptor-interacting protein kinase 1 (RIPK1) has been proposed to mediate pathogenesis of ALS.
Jun Wei   +11 more
doaj   +1 more source

Enteric synucleinopathy: real entity or only a trendy concept?

open access: yesFree Neuropathology, 2020
An accumulating body of literature has emerged in the past 25 years to show that Parkinson’s disease (PD) is not only a disorder of the brain but also of the gastrointestinal tract and more generally of the gut-brain axis. Gastrointestinal symptoms occur
Adrien de Guilhem de Lataillade   +4 more
doaj   +1 more source

NOD1/RIP2 signalling enhances the microglia-driven inflammatory response and undergoes crosstalk with inflammatory cytokines to exacerbate brain damage following intracerebral haemorrhage in mice

open access: yesJournal of Neuroinflammation, 2020
Background Secondary brain damage caused by the innate immune response and subsequent proinflammatory factor production is a major factor contributing to the high mortality of intracerebral haemorrhage (ICH).
Miao Wang   +15 more
doaj   +1 more source

The 17th National Annual Conference on Neurological Infectious Diseases and Cerebrospinal Fluid Cytology of the Chinese Medical Association Neurology Branch was successfully held

open access: yesBrain Hemorrhages, 2021
The 17th National Annual Conference on Neurological Infectious Diseases and Cerebrospinal Fluid Cytology of the Chinese Medical Association Neurology Branch was successfully held in Wuhan, Hubei, China.
Ge Zhang   +5 more
doaj   +1 more source

Standards in neurosonology. Part III [PDF]

open access: yesJournal of Ultrasonography, 2016
The paper presents standards related to ultrasound imaging of the cerebral vasculature and structures. The aim of this paper is to standardize both the performance and description of ultrasound imaging of the extracranial and intracranial cerebral ...
Joanna Wojczal   +5 more
doaj   +1 more source

Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]

open access: yes, 2020
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong   +15 more
core   +1 more source

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