Results 41 to 50 of about 345,763 (186)
Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2H-indazole Hybrids
Pharmaceuticals, 2021 Cancer is the second leading cause of death, after cardiovascular diseases. Different strategies have been developed to treat cancer; however, chemotherapy with cytotoxic agents is still the most widely used treatment approach.Jaime Pérez-Villanueva, Félix Matadamas-Martínez, Lilián Yépez-Mulia, Vadim Pérez-Koldenkova, Martha Leyte-Lugo, Karen Rodríguez-Villar, Francisco Cortés-Benítez, Ana Perla Macías-Jiménez, Ignacio González-Sánchez, Ariana Romero-Velásquez, Juan Francisco Palacios-Espinosa, Olivia Soria-Arteche +11 moredoaj +1 more sourceVulnerability of marine megafauna to global at‐sea anthropogenic threats
Conservation Biology, Volume 40, Issue 1, February 2026.Abstract
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened ...Michelle VanCompernolle, Juliet Morris, Hannah J. Calich, Jorge P. Rodríguez, Sarah A. Marley, Jessica R. Pearce, Briana Abrahms, Katya Abrantes, André S. Afonso, Alex Aguilar, Andrews Agyekumhene, Tomonari Akamatsu, Susanne Åkesson, Nyimale G. Alawa, Joanna Alfaro‐Shigueto, R. C. Anderson, Tycho Anker‐Nilssen, Javier A. Arata, Gonzalo Araujo, Martin C. Arostegui, Haritz Arrizabalaga, Lucy M. Arrowsmith, Marie Auger‐Méthé, Isabel C. Avila, Fred Bailleul, Joanna Barker, Dawn R. Barlow, Adam Barnett, Hector Barrios‐Garrido, Alastair M. M. Baylis, Giovanni Bearzi, Lars Bejder, Eduardo J. Belda, Scott R. Benson, Michael L. Berumen, Sophie Bestley, Natalia P. A. Bezerra, Antonin V. Blaison, Lars Boehme, Steven J. Bograd, Bolaji Dunsin Abimbola, Mark E. Bond, Asunción Borrell, Phil J. Bouchet, Peter Boveng, Gill Braulik, Camrin D. Braun, Stephanie Brodie, Leandro Bugoni, Carlos Bustamante, Steven E. Campana, Susana Cárdenas‐Alayza, Ruth H. Carmichael, Gemma Carroll, Matt I. D. Carter, Filipe R. Ceia, Salvatore Cerchio, Luciana C. Ferreira, Philippine Chambault, Taylor K. Chapple, Patricia Charvet, Elpis J. Chavez, Damien Chevallier, Andre Chiaradia, B. Louise Chilvers, Megan A. Cimino, Bethany L. Clark, C. R. Clarke, Thomas A. Clay, Carl S. Cloyed, Jesse E. M. Cochran, Tim Collins, Enric Cortes, Eduardo Cuevas, David J. Curnick, Peter Dann, P. J. Nico de Bruyn, Asha de Vos, Solène Derville, Maria P. Dias, Bruno Diaz‐Lopez, Kara L. Dodge, Alistair D. M. Dove, Thomas K. Doyle, J. Marcus Drymon, Christine L. Dudgeon, Peter H. Dutton, Ursula Ellenberg, Simon H. Elwen, Louise Emmerson, Edem A. Eniang, Mario Espinoza, Nicole Esteban, Evert Mul, Brian S. Fadely, Annette L. Fayet, Chris Feare, Steven H. Ferguson, Laura Joan Feyrer, Brittany Finucci, Katie R. N. Florko, Jorge Fontes, C. M. Fortuna, Sabrina Fossette, Leila Fouda, Esteban Frere, Mariana M. P. B. Fuentes, Austin J. Gallagher, Pablo Garcia Borboroglu, Claire Garrigue, Pauline Gauffier, Enrico Gennari, Tilen Genov, Elitza S. Germanov, Joan Giménez, Matthew H. Godfrey, Brendan J. Godley, Simon D. Goldsworthy, Matthew Gollock, Victoria González Carman, Natasha J. Gownaris, W. James Grecian, Hector M. Guzman, Mark Hamann, Neil Hammerschlag, Erpur S. Hansen, Mike P. Harris, Gordon Hastie, Danielle E. Haulsee, Elliott L. Hazen, Mads Peter Heide‐Jørgensen, Elizabeth E. Hieb, Jeff W. Higdon, Mark A. Hindell, Jefferson T. Hinke, Xavier Hoenner, G. J. Greg Hofmeyr, Bonnie J. Holmes, Erich Hoyt, Luis A. Huckstadt, Nigel E. Hussey, Charlie Huveneers, Lyn G. Irvine, Rima W. Jabado, David M. P. Jacoby, Audrey Jaeger, Patrick M. Jagielski, Mark Jessopp, Oliver J. D. Jewell, David Jiménez Alvarado, Lance K. B. Jordan, Salvador J. Jorgensen, Benjamin Kahn, Alexandros A. Karamanlidis, Akiko Kato, Lucy W. Keith‐Diagne, M. S. Kiani, Jeremy J. Kiszka, Alison A. Kock, R. Keller Kopf, Carey Kuhn, Peter M. Kyne, Kristin L. Laidre, Fernanda O. Lana, Michelle E. Lander, Matthieu Le Corre, Olivia A. Lee, Ruth H. Leeney, Alexis L. Levengood, J. Jacob Levenson, Marcela Libertelli, Kwang‐Ming Liu, Milagros Lopez Mendilaharsu, Alexandra Loveridge, Christopher G. Lowe, Heather J. Lynch, Bruno C. L. Macena, Alice I. Mackay, Jeffry Madrigal‐Mesén, Mark L. Mallory, Jeffrey C. Mangel, Katherine L. Mansfield, David March, Marianne Marcoux, Helene Marsh, A. D. Marshall, Thomas Mattern, Sara M. Maxwell, Rebecca L. McGuire, Lachlan McLeay, Clive R. McMahon, Séverine Methion, Eva K. M. Meyers, Candice Michelot, Cara Masere, Gianna Minton, Benjamin Morales‐Vela, Gonzalo Mucientes, Hilario Murua, M. A. C. Nicoll, Yuri Niella, Giuseppe Notarbartolo di Sciara, Steffen Oppel, Florian Orgeret, Julie N. Oswald, Ellie Owen, Nathan Pacoureau, Vitor H. Paiva, Daniel M. Palacios, Simone Panigada, Yannis P. Papastamatiou, Guido J. Parra, Sylvia K. Parsons, Donna L. Patterson‐Fraser, S. Hoyt Peckham, Stephen D. Petersen, Lorien Pichegru, Simon J. Pierce, Tânia Pipa, Enrico Pirotta, Pierre Pistorius, Riley A. Pollom, Rui Prieto, Laura Prosdocimi, Klemens Pütz, Nuno Queiroz, John L. Quinn, Jaime A. Ramos, Holly C. Raudino, Angela Recalde‐Salas, ALan F. Rees, Richard D. Reina, Ryan R. Reisinger, Samantha D. Reynolds, Anthony James Richardson, Nicholas G. Riddoch, Federico G. Riet‐Sapriza, James R. Robbins, David P. Robinson, Airam Rodríguez, Tracey L. Rogers, Christoph A. Rohner, Daniela Rojas‐Cañizales, Kevin Ruhomaun, Chandra Salgado Kent, Katsufumi Sato, Kylie L. Scales, Meike Scheidat, Gail Schofield, Fabrizio Serena, Edy Setyawan, Scott A. Shaffer, Brendan D. Shea, Laura Shearer, Marcus Sheaves, Richard B. Sherley, George L. Shillinger, Takahiro Shimada, Mónica A. Silva, Gregory Skomal, Reyd A. Smith, Amy F. Smoothey, Alen Soldo, Emily J. Southall, Antje Steinfurth, D. Bruce Stewart, Joshua D. Stewart, Akinori Takahashi, Vikash Tatayah, Sam Thalmann, Jean‐Baptiste Thiebot, Jesús Tomás, Leigh G. Torres, P. N. Trathan, Fritz Trillmich, Kazuoki Ueda, Frederic Vandeperre, Ralph Eric Thijl Vanstreels, Marisa Vedor, Stella Villegas‐Amtmann, Lauren J. Waller, Matt Waller, Sarah Wanless, Kelly Waples, Cortney A. Watt, Mia Wege, Caroline R. Weir, Randall S. Wells, Paul J. Wensveen, Timothy D. White, Scott D. Whiting, Øystein Wiig, Natalie E. Wildermann, David N. Wiley, Jessica Lauren Williams, Rosie S. Williams, Kenady Wilson, Matthew J. Witt, Freya C. Womersley, David J. Yurkowski, Jie Zhang, Daniel P. Costa, Carlos M. Duarte, Mark G. Meekan, Rob Harcourt, David W. Sims, Graeme C. Hays, Charitha Pattiaratchi, Víctor M. Eguíluz, Ana M. M. Sequeira +309 morewiley +1 more sourceSynthesis and Biological Evaluation of 2H-Indazole Derivatives: Towards Antimicrobial and Anti-Inflammatory Dual Agents
Molecules, 2017 Indazole is considered a very important scaffold in medicinal chemistry. It is commonly found in compounds with diverse biological activities, e.g., antimicrobial and anti-inflammatory agents.Jaime Pérez-Villanueva, Lilián Yépez-Mulia, Ignacio González-Sánchez, Juan Francisco Palacios-Espinosa, Olivia Soria-Arteche, Teresita del Rosario Sainz-Espuñes, Marco A. Cerbón, Karen Rodríguez-Villar, Ana Karina Rodríguez-Vicente, Miguel Cortés-Gines, Zeltzin Custodio-Galván, Dante B. Estrada-Castro +11 moredoaj +1 more sourceBiophysical characterization of the outer membrane polysaccharide export protein and the polysaccharide co-polymerase protein from Xanthomonas campestris [PDF]
, 2014 This study investigated the structural and biophysical characteristics of GumB and GumC, two Xanthomonas campestris membrane proteins that are involved in xanthan biosynthesis. Xanthan is an exopolysaccharide that is thought to be a virulence factor that Bianco, María Isabel, Ielmini, M. V., Ielpi, Luis, Jacobs, Melisa, Salinas, Silvina Rosa, Salvay, Andrés Gerardo +5 morecore +1 more sourceCommunity‐driven variations in snow algae color modulate snow albedo reduction
New Phytologist, Volume 249, Issue 4, Page 1739-1752, February 2026.Summary Snow algae blooms visibly alter snow color and surface energy balance, yet the biological basis of this variability remains unclear. We investigated how pigment composition and community structure shape the optical properties of snow algae blooms of distinct colors – red, orange, and green – co‐occurring within the same snowfield in Glacier ...Pablo Almela, James J. Elser, Anthony Zmuda, Thomas Niehaus, Trinity L. Hamilton +4 morewiley +1 more sourceIntervenção de esportes modificados para melhorar metas de participação e competências de atividade em crianças deambuladoras com paralisia cerebral: um ensaio clínico randomizado
Developmental Medicine &Child Neurology, Volume 68, Issue 1, Page e1-e15, January 2026.Intervenções de esportes modificados para crianças com Paralisia Cerebral: Resumo gráfico. Resumo Objetivo
Avaliar a eficácia de uma intervenção de esportes modificados (Sports Stars Brasil) nos objetivos de participação em atividades físicas de lazer, desempenho e capacidade motora, funções corporais, níveis de atividade física, alfabetização física e Ricardo R. Sousa Junior, Georgina L. Clutterbuck, Rafaela F. Guimaraes, Mariane G. Souza, Luana C. Silva, F. Virginia Wright, Ana Cristina R. Camargos, Hércules R. Leite +7 morewiley +1 more source
