Results 171 to 180 of about 22,194 (215)
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2005
This article is a revision of the first print edition article by Ann D Mitchell, volume 3, pp 144–146, © 1998, Elsevier Inc. who has now sadly deceased.
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This article is a revision of the first print edition article by Ann D Mitchell, volume 3, pp 144–146, © 1998, Elsevier Inc. who has now sadly deceased.
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Sister chromatid exchange and nasopharyngeal carcinoma
International Journal of Cancer, 1989AbstractSister chromatid exchange (SCE) is a genetic indicator of DNA damage in mammalian cells and may afford a sensitive monitor to follow genomic instability of some individuals with fragile chromosomal diseases or malignancies. In studies on the effect of dinitrosopiperazine (DNP), aflatoxin BI (AFBI), methyl‐nitro‐nitroso‐guanidine (MNNG) and ...
G Y, Li, K T, Yao, R, Glaser
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2007
The sister chromatid exchange (SCE) test is a relatively simple assay, sensitive to most mutagenic compounds. Its major disadvantage is that in order to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds ...
Andrzej Wojcik, Günter Obe
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The sister chromatid exchange (SCE) test is a relatively simple assay, sensitive to most mutagenic compounds. Its major disadvantage is that in order to detect SCEs cells must be either treated with the label for one round of replication prior to treatment with the mutagen studied or treated simultaneously, but fixed and harvested following two rounds ...
Andrzej Wojcik, Günter Obe
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Sister chromatid exchange and gene mutation
Cytogenetic and Genome Research, 1982The parallel induction of sister chromatid exchange (SCE) and single-gene mutation was quantified in Chinese hamster ovary cells following exposure to nine different physical or chemical agents representing a wide variety of inducing lesions. For each agent, the frequency of induced SCE was linearly related to the induction of mutation, but the ...
A V, Carrano, L H, Thompson
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Statistical evaluation of sister chromatid exchanges
Human Genetics, 1984Log-linear models are fitted to sister chromatid exchange (SCE) scores in order to test the significance of the differences in SCE scores observed between individuals or between experimental treatments. The analysis is performed at the level of chromosome groups. In each single test all measurements from all chromosome groups, both from the control and
P, Vercauteren +4 more
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Sister chromatid exchange in malignant lymphomas
Cancer Genetics and Cytogenetics, 1984Sister chromatid exchange (SCE) was evaluated in peripheral lymphocytes from 20 untreated patients with malignant lymphomas: 6 with Hodgkin's disease (HD), 14 with non-Hodgkin lymphoma (NHL), and 5 with lymphadenitis. The mean SCE frequency (+/- SE) was: 11.2 +/- 0.6, 11.0 +/- 0.6, and 7.2 +/- 0.3 for HD, NHL, and lymphadenitis patients, respectively ...
I, Slavutsky +4 more
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Sister chromatid exchange in childhood malignancies
Teratogenesis, Carcinogenesis, and Mutagenesis, 1983Sister chromatid exchange studies were conducted in 53 children with malignant diseases. Children with acute lymphoid leukemia in long remission, already off chemotherapy or on maintenance therapy, had normal SCE values, whereas those receiving intensive cytostatic therapy showed elevated levels.
J, Szollár, G, Fekete, D, Schuler
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The Sister Chromatid Exchange (SCE) Assay
2014A fully optimized staining method for detecting sister chromatid exchanges in cultured cells is presented. The method gives reproducibly robust quantitative results. Sister chromatid exchange is a classic toxicology assay for genotoxicity and for detecting alterations to the biochemistry underlying cellular homologous recombination.
Dawn M, Stults +2 more
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Sister chromatid exchanges in leukemic patients
Cancer Genetics and Cytogenetics, 1985Sister chromatid exchange (SCE) was studied in PHA-stimulated peripheral blood lymphocytes from 36 newly diagnosed and untreated leukemic patients: 16 with acute lymphoblastic leukemia (ALL), 10 with acute nonlymphocytic leukemia (ANLL), and 10 with chronic myelocytic leukemia (CML). The metaphases analyzed show no chromosomal abnormalities.
I, Larripa +3 more
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Automatic detection of sister chromatid exchange
[1988 Proceedings] 9th International Conference on Pattern Recognition, 2003Sister chromatid exchange (SCE) is an interchange of genetic material between replication products at homologous loci. Various chemical agents or other environmental physical factors can cause SCE at concentrations insufficient to produce other significant change in chromosome morphology. A method for automatic detection of SCE is presented.
Liang He, Zhenming Chai
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