Results 71 to 80 of about 26,472 (265)

Heavy Metal Contamination in Chocolates and Candies: Sources, Health Risks, and Analytical Insights

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
The presence of heavy metals in chocolates and candies poses growing public health concerns, particularly for children who are frequent consumers. This review consolidates evidence on the occurrence, sources, toxicological impacts, and analytical monitoring of metals, including Pb, Cd, Hg, As, Cr, Ni, and Al, in confectionery products.
Mahmood Ahmed   +12 more
wiley   +1 more source

In vitro cytotoxic and genotoxic effects of newly synthesised boron ionic liquids

open access: yesBiotechnology & Biotechnological Equipment, 2019
In this study, new molecules containing boron were added to the family of ionic organic compounds, in particular, ionic liquids with a cationic center. This study aimed to determine the cytotoxic and genetic effects of a total of four newly synthesised ...
Sibel Bayil Oguzkan   +4 more
doaj   +1 more source

Investigation of In-ovo cytogenetic effect of Levofloxacin

open access: yesThe Iraqi Journal of Veterinary Medicine, 2018
This study was carried out to investigate the cytogenetic effect of Levofloxacin after In-ovo inoculation. Forty eight fertilized eggs were used, divided equally into eight groups and inoculated through shell puncture above air cell with materials in ...
Marwa H. N.
doaj   +1 more source

Extracellular Vesicle‐Packaged circTAX1BP1 from Cancer‐Associated Fibroblasts Regulates RNA m6A Modification through Lactylation of VIRMA in Colorectal Cancer Cells

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
This study reveals that CAFs‐derived EVs enriched with circTAX1BP1 drive CRLM by promoting VIRMA lactylation and SP1/TGF‐β signaling, creating a positive feedback loop via ITGA11+ myCAFs. Targeting EV‐circTAX1BP1 and TGF‐β disrupts this loop, offering a novel therapeutic strategy for CRLM.
Jia‐nan Tan   +12 more
wiley   +1 more source

Terminalia catappa, an anticlastogenic agent against MMS induced genotoxicity in the human lymphocyte culture and in bone marrow cells of Albino mice

open access: yesEgyptian Journal of Medical Human Genetics, 2014
Background: Terminalia catappa has been used as a folk medicine for treating dermatitis, hepatitis as well as other diseases in India. It possesses anticancer, antioxidant as well as anticlastogenic characteristics.
Mohammad Sultan Ahmad   +4 more
doaj   +1 more source

Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange [PDF]

open access: yes, 2012
Most spontaneous DNA double-strand breaks (DSBs) arise during replication and are repaired by homologous recombination (HR) with the sister chromatid. Many proteins participate in HR, but it is often difficult to determine their in vivo functions due to ...
Aguilera López, Andrés   +7 more
core   +1 more source

ATRX: From Chromatin Remodeling to Disease

open access: yesgenesis, Volume 63, Issue 6, December 2025.
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta   +1 more
wiley   +1 more source

Assessment of chromosome stability in boars.

open access: yesPLoS ONE, 2020
Chromosome instability adversely affects animal fertility and reproduction. Analysis of instability can be a valuable diagnostic tool. Helpful tests for assessment of instabilities include the sister chromatid exchange assay, identification of fragile ...
Ewa Wójcik, Agnieszka Sokół
doaj   +1 more source

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]

open access: yes, 1993
A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core   +2 more sources

The Multifactorial Causes of Down Syndrome During Pregnancy: A Narrative Review of Genetic, Environmental, and Maternal Influences

open access: yesHealth Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Chromosomal nondisjunction is the primary etiology of Down syndrome; however, genetic variations, environmental causes, and maternal etiologies also contribute to a great extent. The objective of this review is to evaluate these multifaceted factors during pregnancy.
Md. Sohel Rana   +2 more
wiley   +1 more source

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