Detection of Chromosomal Inversions Using Non-Repetitive Nucleic Acid Probes [PDF]
A method and a kit for the identification of chromosomal inversions are described. Single-stranded sister chromatids are generated, for example by CO-FISH.
Bailey, Susan M. +4 more
core +1 more source
Chromosome segregation in plant meiosis [PDF]
, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico +4 more
core +2 more sources
Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication
Advanced Science, Volume 13, Issue 8, 9 February 2026.EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu +12 more
wiley +1 more source
Establishment of Sister Chromatid Cohesion [PDF]
Current Biology, 2009 The process of sister chromatid pairing, or cohesion establishment, is coupled to DNA replication and fundamental to proper chromosome segregation and cell viability. In the past year, several articles have provided important new insights into cohesion establishment, an activity predicated on the acetyltransferase Ctf7/Eco1. Here, I review new findings
openaire +2 more sources
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
, 2014 The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +2 more sources
Cell Proliferation, Volume 59, Issue 2, February 2026.Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source
Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
New Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr +8 more
wiley +1 more source
Separase and Roads to Disengage Sister Chromatids during Anaphase. [PDF]
Int J Mol Sci, 2023 Konecna M, Abbasi Sani S, Anger M.
europepmc +1 more source
A non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
The EMBO JournalThe 16-subunit Constitutive Centromere-associated Network (CCAN)-based inner kinetochore is well-known for connecting centromeric chromatin to the spindle-binding outer kinetochore.
Lu Yan +12 more
doaj +1 more source
Sister chromatids separate during anaphase in a three-stage program as directed by interaxis bridges. [PDF]
Proc Natl Acad Sci U S A, 2022 Chu L +4 more
europepmc +1 more source